Inland navigation is hardly ever used to transport cargo in cities. In most urban areas, it is performed almost exclusively via road transport, with the virtual exclusion of rail and inland transport. Research and implementation projects in several European cities have shown that employing inland navigation is a viable alternative for road transport in urban areas. The research involved a case study of transporting the same number of 40-foot containers by inland waterway and road and then comparing the results in terms of transport time, transport costs, and carbon dioxide emissions between two metropolitan areas in Poland. The article shows that River Information Services (RIS) system can contribute to improving freight transport efficiency not only on longer routes, but also in urban and inter-urban conditions. The findings were that inland shipping is much cheaper and more environmentally friendly, but transport takes much longer and is not always possible due to insufficient waterway infrastructure. The paper can be used as a road map to proceed with new approach to planning urban and inter-urban logistics, with the use of inland navigation supported by the RIS system. The study delivers evidence that the main benefits of using RIS for urban logistics are: optimization of the cargo route, improved supervision and control of cargo transport, optimization of inter-branch transport, optimization of the use of fleet, more efficient use of technical infrastructure of waterways, combination of many recipients/senders into one transport, and reduction of administrative barriers.