“…Generally, no mark of the map belongs to a cluster, but a mark may belong to one or more clusters. Mathematically, the graph G ′ is the union of mark clusters G m , that is, F I G U R E 11 The Venn diagram depicting the relations between clusters of attributes (qualitative marks) and clusters of maximum and minimum marks, where P max.n and P min.n are the marks indicating the nth local maximum and local minimum values of the number of patients, respectively; R max.n and R min.n are the marks indicating the n th local maximum and local minimum values of rainfall, respectively; H max.n and H min.n are the marks indicating the n th local maximum and local minimum values of humidity, respectively; T max.n and T min.n are the marks indicating the n th local maximum and local minimum values of temperature, respectively F I G U R E 12 The graph representing the dataset of hand-foot-mouth disease in Binhduong province during 2012-2014, 1,25 where red bars represent the number of patients, blue bars represent rainfall, green bars represent humidity, and pink bars represent average temperature called maximum or minimum cluster, other marks are grouped into different clusters. Technically, differential algorithm is applied to indicate maximum or minimum marks associating with their reference values.…”