2024
DOI: 10.1038/s41598-024-79904-z
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Integrative multi-omics analysis to gain new insights into COVID-19

Setegn Eshetie,
Karmel W. Choi,
Elina Hyppönen
et al.

Abstract: Multidimensional host and viral factors determine the clinical course of COVID-19. While the virology of the disease is well studied, investigating host-related factors, including genome, transcriptome, metabolome, and exposome, can provide valuable insights into the underlying pathophysiology. We conducted integrative omics analyses to explore their intricate interplay in COVID-19. We used data from the UK Biobank (UKB), and employed single-omics, pairwise-omics, and multi-omics models to illustrate the effec… Show more

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