Swine flu is a highly contagious respiratory viral disease which is caused by influenza a virus. The disease can be found everywhere in the world especially in those peoples rearing pigs. The virus can circulate between human, avian, and swine. It spread through aerosol transmission, via contact with affected pigs and contaminated objects with the virus. Different factors including immuno suppression predispose individuals to the disease. Swine influenza manifested by coughing, anorexia and lethargy in pigs while sudden fever and cough in human. The disease can be diagnosed either by laboratory or by observing signs and symptoms. It has a devastating effect on the economy and health of the communities even though it can be prevented and controlled with different measures like vaccines and antiviral drugs. Recently, active case reported in Addis Ababa, Ethiopia. So, due to its highly spread and economic importance it should have to be reported immediately to authorities if the cases have been seen and care should be taken if person showing the sign of the disease is observed.