Interaction study of three overlapping synthetic peptides belonging to E2 protein of GBV-C/HGV with liposomes as biomembrane models

Abstract

Abstract. In this work we studied by DSC the interaction of three antigenic overlapping peptides belonging to the E2 envelope protein of Hepatitis G virus, namely E2(39-53), E2(32-53) and E2(26-53), with liposomes of different lipid composition (DPPC, DMPC and DMPG) as biomembrane models. The effect of the three selected peptides on the thermotropic behaviour of lipid bilayers has been evaluated.