Interactions between Gabapentin and Cisatracurium in Experimental Animals and in Patients Undergoing Spinal Surgeries : Pharmacological and Clinical Study
Abstract:Background: gabapentin was originally discovered over 40 years ago by the Japanese, who initially were looking for an antispasmodic or muscle relaxant, but, later it was used as an antiepileptic and multimodal perioperative drug. Objective of this randomized study is to assess the some cardiovascular effects of gabapentin as well as its effect on the neuromuscular blockade induced by Cisatracurium. The interactions between both of them was also done in cats and rats & in patients undergoing elective spinal sur… Show more
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