Interactions between pH-sensitive liposomes and model membranes

pH-Sensitive fusogenic polymer-modified liposomes as a carrier of antigenic proteins for activation of cellular immunity

“…In this study, we used a mixture of EYPC and DOPE as liposomal lipids because inclusion of DOPE is shown to increase the fusion ability of liposomes [24]. We examined the fusion abilities of these polymer-modified liposomes using resonance energy transfer between NBD-labeled and Rh-labeled lipids in the liposome membranes.…”

Interaction of an Endosomolytic Polyamidoamine ISA23 with Vesicles Mimicking Intracellular Membranes: A SANS/EPR Study

“…It is acknowledged that although the composition of the isolated plasma, endosomal and lysosomal membranes has been widely reported [10][11][12][13][14][15] ( Table 1 and Scheme 1), endocytosis is a complex process [16] and the lipid composition of each delimiting membrane will vary from one cell type to another. Moreover, asymmetry of lipid composition across the bilayer is an important biochemical regulator [16] and the many other components, such as cholesterol and proteins are essential for normal physiological behavior.…”

Transfection mediated by pH-sensitive sugar-based gemini surfactants; potential for in vivo gene therapy applications

“…Consequently, strategies have been developed to trigger the timely removal of this PEG coating to accomplish effective cellular transfection. These strategies involve release of either the PEG group via pH sensitive cleavage [25][26][27] or the PEG-lipids as such, relying on acyl chain lengthdependent lipid exchange [28,29].…”