Interactions du benzoate d'oestradiol et de la progesterone sur le developpement de l'oviducte de caille (Coturnix coturnix japonica)

Sandoz, Daniel; Boisvieux‐Ulrich, Emmanuelle; Laugier, Christian; Brard, E

doi:10.1016/0016-6480(75)90168-9

Cited by 27 publications

(9 citation statements)

References 14 publications

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“…(iv) Ovalbumin is not inducible by primary E2 stimulation in this system. These data confirm previous work (44).…”

supporting

confidence: 83%

Mechanism of estrogen action: Indirect effect of estradiol-17β on proliferation of quail oviduct cells

Laugier¹,

Pageaux²,

Soto³

et al. 1983

Proc. Natl. Acad. Sci. U.S.A.

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Experimental data were collected to test whether the effect of estrogens required a direct action of the steroid on their target cells for induction of (i) cell multiplication and (ii) celltype-specific protein synthesis. Ovariectomized quails were perfused for 24 hr with several doses of estradiol-17.8 (E2) (0.05-6.8 ng/min) through either thejugular vein or the portal vein. E2 plasma concentrations increased progressively when the perfusion rate through thejugular vein was 0.5 ng/min and higher. With the portal vein, by contrast, E2 plasma concentrations increased over the concentration in unperfused ovariectomized animals only when the perfusion rate was above 2 ng/min. An increase in DNA concentration per oviduct was observed regardless of the route of administration and the rate of perfusion, starting at 0.5 ng/min. Nuclear estrophilins increased when E2 was perfused through the jugular vein at rates of 0.5 ng/min or greater. This same parameter was not increased in oviducts of quail perfused through the portal vein even at a perfusion rate of 2.0 ng/min. Progestophilins were induced in the oviducts of quail perfused through thejugular vein at rates of 2 ng/min and above; on the other hand, progestophilins were induced in birds perfused through the portal vein at rates above 2 ng/min. Ovalbumin was not induced in quail oviducts at any rate and route of perfusion. The induction of the synthesis of cell-type-specific protein (progestophilins, in this case) seems to require, however, the direct action of E2. The E2 concentrations effecting the induction of progestophilins were higher than those necessary to effect the proliferation of oviduct cells. These results suggest that the E2 effect on cell proliferation is indirect, it involves an intermediary step at the liver, and it does not require increased concentration of nuclear estrophilins.An extensive literature regarding the mechanism of estrogen action in the oviduct of birds is available (1-4). The central argument postulated for mammals by Jensen's group and later extended to birds and other phyla suggests that the full response of these target tissues to the administration of estrogen is direct, regardless of the parameter measured (5,6). Among the many markers that have been linked to this putatively direct effect, the more thoroughly studied are (i) the induction of certain proteins [ovalbumin, prolactin, creatine kinase, progesterone receptors (progestophilins), and others] (7-15), (ii) the inhibition of the synthesis of gonadotropins and other cell proteins (16,17), and (iii) the proliferative response of the uterus (18)(19)(20), vagina (21), mammary glands (22), bird oviduct (23, 24), and a number of estrogen-sensitive tumors (25) and cultured cell lines (13)(14)(15)(26)(27)(28).Despite the abundant bibliography on these subjects, whether the effect of estrogens on cell multiplication is exerted through a direct or indirect pathway remains a controversial subject (21,22,(28)(29)(30). The latter possibility implies that at least one interme...

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“…(iv) Ovalbumin is not inducible by primary E2 stimulation in this system. These data confirm previous work (44).…”

supporting

confidence: 83%

Mechanism of estrogen action: Indirect effect of estradiol-17β on proliferation of quail oviduct cells

Laugier¹,

Pageaux²,

Soto³

et al. 1983

Proc. Natl. Acad. Sci. U.S.A.

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“…In previous reports we have shown that in castrated quail oestradiol benzoate (10 pg daily) reproduces condi¬ tions compatible with normal oestrogen stimulation (Laugier, Claustrat & Brard, 1978) and induces cell proliferation, ciliogenesis and tubular gland forma¬ tion Sandoz et al 1975). Progesterone is required for mucous cell differentia¬ tion as well as for the synthesis and accumulation of egg-white proteins Sandoz et al 1975;Sandoz, Boisvieux-Ulrich, Laugier & Brard, 1976). …”

Section: Discussionmentioning

confidence: 94%

Development of the oviduct in quail during sexual maturation in relation to plasma concentrations of oestradiol and progesterone

Pageaux¹,

Laugier²,

Pal³

et al. 1984

Journal of Endocrinology

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The macromolecular content (DNA, soluble proteins and ovalbumin) of the magnum and the plasma concentrations of oestradiol and progesterone were studied during sexual development of the Japanese quail. Rapid growth and differentiation of the magnum began between 21 and 28 days of age and rapidly reached the laying stage in about 20 days. This rapid change in magnum size occurred in a stepwise manner: cellular proliferation was observed first, followed by the synthesis and accumulation of specific proteins. Just before and during magnum growth, plasma oestradiol and progesterone concentrations followed different patterns: the initiation of epithelial cell proliferation was preceded by a sharp decrease in plasma progesterone. Maximum cell division occurred while plasma progesterone levels continued to decrease slightly; at the same time, oestradiol increased from 0.098 to 0.453 nmol/l. The decrease and finally the cessation of cell proliferation and the concomitant increase in ovalbumin concentration were related to almost constant levels of plasma oestradiol and increasing levels of plasma progesterone. Further development of the magnum (above 2.3 g weight) involving only the accumulation of secretory products was associated with an increased value of plasma progesterone. These data are consistent with the hypothesis that there are multiple hormonal signals controlling cell proliferation and synthesis of egg-white proteins in the oviduct. Progesterone may be one of the key signals that regulates the initiation of oviduct growth in the quail.

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“…Even when it can be induced by estrogen injections, such as in immature bird oviduct [3,44,45,68,70], all steps of ciliogenesis are found simultaneously in the same oviduct ( Fig. Even when it can be induced by estrogen injections, such as in immature bird oviduct [3,44,45,68,70], all steps of ciliogenesis are found simultaneously in the same oviduct ( Fig.…”

Section: Centriolooenesismentioning

confidence: 99%

“…The main difficulty in isolation and analysis of generative complexes and centriolar precursors is that ciliogenesis is not synchronous in metazoan ciliated epithelium. Even when it can be induced by estrogen injections, such as in immature bird oviduct [3,44,45,68,70], all steps of ciliogenesis are found simultaneously in the same oviduct ( Fig. 1).…”

Section: Centriolooenesismentioning

confidence: 99%

Development and functions of the cytoskeleton during ciliogenesis in metazoa

Lemullois¹,

Boisvieux‐Ulrich²,

Lainé³

et al. 1988

Biology of the Cell

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The different steps of ciliogenesis occurring in quail oviduct were compared to the ciliogenesis pattern described in other metazoan species. Centrioles are generated according to pathways that are found within the same cell: the centriolar and the acentriolar pathways. In the acentriolar pathway, centrioles are generated in the Golgi area, without contact with the preexisting centrioles of the centrosomes, and they migrate toward the apical membrane. The control of this polarized migration was studied by means of several drugs (colchicine, nocodazol, taxol, cytochalasin D, benzodiazepines) and immunocytochemistry. It was suggested that an actin-myosin system was involved in the migration of centrioles, whereas labile microtubules were not necessary. Basal bodies must dock with plasma membrane or cytoplasmic vesicles for the initiation of axonemal microtubule polymerization. This signal is necessary even in the presence of taxol.

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Interactions du benzoate d'oestradiol et de la progesterone sur le developpement de l'oviducte de caille (Coturnix coturnix japonica)

Cited by 27 publications

References 14 publications

Mechanism of estrogen action: Indirect effect of estradiol-17β on proliferation of quail oviduct cells

Mechanism of estrogen action: Indirect effect of estradiol-17β on proliferation of quail oviduct cells

Development of the oviduct in quail during sexual maturation in relation to plasma concentrations of oestradiol and progesterone

Development and functions of the cytoskeleton during ciliogenesis in metazoa

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