“…2 In many small-to medium-sized hospitals, the infrastructure required for the ongoing evaluation and monitoring of patients with post-tPA stroke may not be available. 3 In addition, the absence of neurointensive or neurosurgical resources to manage post-tPA complications, such as symptomatic intracranial hemorrhage (sICH), may result in lower rates of tPA use. 4 The drip and ship method, whereby tPA is administered locally in an emergency department followed by transfer to a stroke center, aims to increase the rates of tPA use and its timely administration.…”