Interdisciplinary Electrochemistry STEM-Lab Activities Replacing the Single Disciplinary Electrochemistry Curriculum for Secondary Schools

Karpudewan, Mageswary; Huri, Noor Haslina Daman

doi:10.1021/acs.jchemed.2c00469

Cited by 5 publications

(1 citation statement)

References 37 publications

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“…Additionally, nontraditional chemistry courses such as materials chemistry and chemical biology, now offered in some departments, interface chemistry with other fields of science and provide an excellent opportunity to develop expertise in working and transferring knowledge between chemistry and other fields. Indeed, chemists have been involved in cross-disciplinary studies, exemplified by interdisciplinarity, − and this will continue as an integral part of chemistry education.…”

Section: Introductionmentioning

confidence: 99%

Bioorthogonal Metabolic Labeling Experiments to Introduce Undergraduate Students to Interdisciplinarity at the Interface of Chemistry and Biology

Fura,

Oluwole,

Hakim

et al. 2023

J. Chem. Educ.

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Chemists have always designed and deployed crossdisciplinary approaches that interface chemistry with other disciplines to proffer solutions to many human problems. We designed a laboratory experiment that implements chemistry concepts in a biological model to prime undergraduate students to appreciate interdisciplinarity as an approach to solving complex problems in contemporary society. The experiments can also be implemented with graduate students transitioning to chemical biology research. The experiment introduces students to classical and emerging chemistry and molecular biology techniques�mammalian cell culture, bioorthogonal metabolic labeling, azide−alkyne cycloaddition reaction ("click" chemistry), microplate photometry, gel electrophoresis, and far-western blot analysis�that are routinely used in research at the interface of chemistry and biology. The students cultured a Chinese hamster ovary cell line (CHO-K1) and metabolically labeled the cellular sialoglycans with azide groups. Next, they used a click chemistry reaction to bioconjugate a fluorogenic molecule to the labeled sialoglycans, enabling the detection of the glycans using microplate photometry or far-western blot analysis. The experiment created a context for a first-hand demonstration of bioorthogonal chemical reaction, a concept novel to most undergraduates with traditional chemistry (organic, inorganic, physical chemistry, and analytical) background. The experience allows the students to apply and connect organic chemistry, bioanalytical chemistry, and molecular biology concepts while learning techniques such as microplate reading, SDS PAGE, and western blot imaging that are indispensable to the growing fields of drug discovery, chemical toxicology, chemical biology, and molecular biology. This experiment is ideal for preparing and motivating students to pursue future research opportunities at the interface of chemistry and biology.

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Section: Introductionmentioning

confidence: 99%

Bioorthogonal Metabolic Labeling Experiments to Introduce Undergraduate Students to Interdisciplinarity at the Interface of Chemistry and Biology

Fura,

Oluwole,

Hakim

et al. 2023

J. Chem. Educ.

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Do You Want to Make a Battery? Insights from the Development and Evaluation of a Chemistry Public Engagement Activity

O’Donoghue,

Doménech,

Tully

et al. 2024

J. Chem. Educ.

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Chemistry is often associated with formal learning environments and has been described as overly serious by the general public, lacking some of the fun and energy of other sciences. However, it is difficult to provide hands-on chemistry activities outside the lab and other formal learning environments. Here, a simple electrochemistry based activity has been used for public engagement using household items and play dough to create a fun and playful experience for all ages. The benefits afforded by outdoor learning for developing curiosity and interest in science has also been explored through different event formats. The use of a "Smiley Stand" with "emojis" for gathering participant feedback was successfully deployed alongside interviews with the "Ambassadors" who facilitated the activity. Overall, it was found that the activity encouraged two-way conversations between the participants and the ambassadors, with few negative responses and many positive ones received. The activity also impacted the ambassadors' own view of science.

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STEM-PT Traveler, a game-based approach for learning elements of the periodic table: an approach for enhancing secondary school students’ motivation for learning chemistry

Mohammed Naaim,

Karpudewan

2024

Chem. Educ. Res. Pract.

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Interdisciplinary Electrochemistry STEM-Lab Activities Replacing the Single Disciplinary Electrochemistry Curriculum for Secondary Schools

Cited by 5 publications

References 37 publications

Bioorthogonal Metabolic Labeling Experiments to Introduce Undergraduate Students to Interdisciplinarity at the Interface of Chemistry and Biology

Bioorthogonal Metabolic Labeling Experiments to Introduce Undergraduate Students to Interdisciplinarity at the Interface of Chemistry and Biology

Do You Want to Make a Battery? Insights from the Development and Evaluation of a Chemistry Public Engagement Activity

STEM-PT Traveler, a game-based approach for learning elements of the periodic table: an approach for enhancing secondary school students’ motivation for learning chemistry

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