2023
DOI: 10.1186/s12879-023-08327-4
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Interferon-γ release assay and mantoux response in infants with tuberculous meningitis in low and intermediate burden countries

Abstract: Aim Until now, the performance of interferon-γ release assay (IGRA) and Mantoux tests remains unclear in infant tuberculous meningitis (TBM). Therefore, a systematic review is performed to evaluate the sensitivity of IGRA and Mantoux tests for the diagnosis of infant TBM in low and intermediate tuberculosis (TB) burden countries, while following PRISMA. Methods Several databases, including PubMed, EBSCO, Embase, Scopus, Web of Science, ClinicalTria… Show more

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