Intermediate Cystinosis

Nithiyanandam, Sangeetha; Parthasarathy, Manisha; Katturajan, Ramkumar; Gopalakrishnan, Abilash Valsala; Sabina, Evan Prince

doi:10.1007/978-3-319-66816-1_1761-1

Cited by 1 publication

(2 citation statements)

References 12 publications

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“…IR and 13 C-NMR Caesalpinianone's infrared spectra revealed strong absorption bands at 3394 (OH), 1641 (CO), and 1612 (CC) cm 1 . All 16 carbon resonances may be seen in the 13C NMR spectrum (CD3OD, 75 MHz) of carbon number 1.…”

Section: Liquid Chromatography-mass Spectrometry Graphmentioning

confidence: 99%

“…This effect was particularly evident in the context of acetaminophen (APAP)-induced spleen and cardiotoxicity, where the extract played a pivotal role in restoring tissue morphology. [13] Although C. bonducella is often used in conventional medicine, relatively less documented systematic pharmacological research has evaluated its analgesic effects. Subbiah et al (2019) highlighted t he medicinal characteristics of several components of C. bonducella L, specifically emphasizing the seed and shell.…”

Section: Abstract a R T I C L E I N F Omentioning

confidence: 99%

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Evaluating The Analgesic Activity of Leaf, Stem Bark Extract And Isolated Nutraceuticals of <i>Caesalpinia Bonducella L (Roxb.)</i>

B. J.,

M. B.,

et al. 2024

Int. J. Pharm. Sci. Drug Res.

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The objective of this study was to evaluate the analgesic potential of Caesalpinia bonducella L (Roxb.) by evaluating the efficacy of leaf and stem bark extracts and isolated nutraceuticals. Nutraceuticals were isolated via column chromatography and characterized using IR and NMR. Analgesic activities were assessed in vivo using the hot plate, capsaicin-induced pain, and tail flick tests on 36 albino mice across nine groups. Phytochemical screening revealed flavonoids and polyphenols. Pure nutraceuticals displayed superior analgesic properties compared to the control. Ethanol extracts of Caesalpinia bonducella leaf and bark exhibited higher analgesic efficacy than other extracts and the control (P<0.05). The study suggests the plant's potential in the nutraceutical field, highlighting its therapeutic value and positioning it as a valuable resource for India's nutraceutical sector.

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Section: Liquid Chromatography-mass Spectrometry Graphmentioning

confidence: 99%

Section: Abstract a R T I C L E I N F Omentioning

confidence: 99%