Intermediate host specificity in Schistosoma mansoni

Basch, Paul F.

doi:10.1016/0014-4894(76)90022-9

Cited by 110 publications

(57 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Strains of B. glabrata may differ in their abilities to suppress an S. mansoni infection with some strains serving as compatible or susceptible hosts, and others demonstrating a resistant phenotype [3,4]. When infective S. mansoni larvae penetrate a resistant host, blood cells known as hemocytes form a multilayered cellular encapsulation around the parasite resulting in larval death, usually within 24 hr postinfection [5].…”

Section: Introductionmentioning

confidence: 99%

Regulation of hydrogen peroxide release in circulating hemocytes of the planorbid snail Biomphalaria glabrata

Humphries

Yoshino

2008

Developmental & Comparative Immunology

View full text Add to dashboard Cite

Biomphalaria spp. serve as obligate intermediate hosts for the human blood fluke Schistosoma mansoni. Following S. mansoni penetration of Biomphalaria glabrata, hemocytes of resistant snails migrate towards the parasite, encasing the larva in a multicellular capsule resulting in its destruction via a cytotoxic reaction. Recent studies have revealed the importance of hydrogen peroxide and nitric oxide (H 2 O 2 , NO) in parasite killing [1,2]. It is assumed H 2 O 2 and NO production is tightly regulated although the specific molecules involved remain largely unknown. Consequently, the potential role of cell signaling pathways in B. glabrata hemocyte H 2 O 2 production was investigated by evaluating the effects of specific inhibitors of selected signaling proteins. Results suggest that both ERK and p38 MAPKs are involved in the regulation of B. glabrata H 2 O 2 release in response to stimulation by PMA and galactose-conjugated BSA. However, the involvement of the signaling proteins PKC, PI 3 kinase and PLA 2 differs between PMA-and BSA-gal-induced H 2 O 2 production.

show abstract

Section: Introductionmentioning

confidence: 99%

Regulation of hydrogen peroxide release in circulating hemocytes of the planorbid snail Biomphalaria glabrata

Humphries

Yoshino

2008

Developmental & Comparative Immunology

View full text Add to dashboard Cite

show abstract

“…The study of invasive Biomphalaria species acquires an additional importance due to their potential role as intermediate hosts for Schistosoma mansoni that impact human health in tropical and subtropical countries (Basch, 1976;Mandahl-Barth, 1957;Morgan et al, 2001). While factors such as dispersion by floods, plants, aquarium fish shipment, and aquatic birds' migration are linked to the widespread distribution of this intermediate host, other environmental factors regulate their abundance and establishment in new areas.…”

Section: Introductionmentioning

confidence: 99%

Predicting the spatial distribution of Biomphalaria straminea, a potential intermediate host for Schistosoma mansoni, in China

Habib

Guo

et al. 2016

Geospat Health

View full text Add to dashboard Cite

Schistosomiasis is one of the most prevalent parasitic diseases impacting human health in the tropics and sub-tropics. The geographic distribution of Schistosoma mansoni, the most widespread species, includes areas in Africa, the Middle East, South America and the Caribbean. Snails of the genus Biomphalaria act as intermediate host for S. mansoni. Biomphalaria straminea is not indigenous in China but was accidentally introduced to Hong Kong from South America and has spread to other habitats in the southern parts of the country. This species is known for its great dispersal capacity that highlights the importance of the snail as a potential host for S. mansoni in China. In this connection, although no such infection has been recorded in the field so far, the continuous expansion of China's projects in endemic areas of Africa and import of the infection via returning workers or visitors deserve attention. The purpose of this study was to map and predict the spatial distribution of B. straminea in China. Snail occurrence data were assembled and investigated using MaxEnt software, along with climatic and environmental variables to produce a predictive risk map. Of the environmental variables tested, the precipitation of warmest quarter was the most contribution factor for snail's spatial distribution. Risk areas were found in southeastern China and it is expected that they will guide policies and control programmes to potential areas area of snail abundance and used for spatial targeting of control interventions for this invasive species.

show abstract

“…Pour chaque température choisie, 20 souris sont exposées à l'infestation transcutanée au niveau abdominal selon la technique d' Erikson (1974). Cinq semaines après l'infestation, les souris sont perfusées pour le comptage des schistosomes adultes (technique de Duwall et Dewitt, 1967 (Basch, 1976). Nous concluons de cette expérience que les B. glabrata des mares de la GrandeTerre sont réceptifs à l'infestation par S .…”

Section: -Infectivité Des Cercairesunclassified

Recherche des facteurs susceptibles d’empêcher la réalisation du cycle deSchistosoma mansonidans les mares de la Grande Terre de Guadeloupe (Antilles françaises)

Thèron

Pointier

1985

Ann. Parasitol. Hum. Comp.

View full text Add to dashboard Cite

RÉSUMÉ. Des enquêtes effectuées dans les mares et étangs de la Grande-Terre de Guadeloupe ont montré l'absence de transmission de Schistosoma mansoni malgré la présence de conditions de milieu apparemment favorables. Quatre hypothèses expliquant l'absence de toute transmission ont été envisagées et étudiées : 1 -Présence de populations de Biomphalaria glabrata non susceptibles à l'infestation par S. man soni. 2 -Conditions de milieu défavorables à la survie des Mollusques parasités. 3 -Conditions de milieu défavorables à la production, à la survie et à l'infectivité des cercaires de S. mansoni. -Processus empêchant la contamination des Mollusques.Les résultats obtenus montrent que la transmission de la schistosomose à S. mansoni est possible dans les mares et étangs de Grande-Terre. Seul, le comportement humain est responsable de l'absence de transmission actuelle dans les collections d'eau de cette région. L'homme interrompt le cycle parasitaire en préservant au maximum les mares et étangs de toute pollution fécale. Researches on factors responsible for the non-transmission of Schistosoma mansoni in the ponds of Grande Terre of Guadalupe (French West Indies). SUMMARY. Different surveys which have been conducted in ponds and pools in the GrandeTerre of Guadalupe, have demonstrated the absence of Schistosoma mansoni transmission in spite of apparent favourable ecological conditions. Four hypothesises can explain this absence of transmission : 1 -the presence of Biomphalaria glabrata populations non-susceptible to the infestation by S. mansoni. 2 -Ecological conditions unfavourable to the survival of parasitized snails. 3 -Ecological conditions unfavourable to the production, survival and infectivity of the S. mansoni cercariae. 4 -Factors causing the non contamination of the snails. The results show that the transmission of schistosomiasis mansoni is possible in the ponds and pools of Grande Terre. Only human behaviour is responsible for the absence of actual trans mission in the waterbodies of this area. Man breaks the life-cycle of the parasite by avoiding all fecal pollution and therefore all snail contamination.

show abstract

Intermediate host specificity in Schistosoma mansoni

Cited by 110 publications

References 57 publications

Regulation of hydrogen peroxide release in circulating hemocytes of the planorbid snail Biomphalaria glabrata

Regulation of hydrogen peroxide release in circulating hemocytes of the planorbid snail Biomphalaria glabrata

Predicting the spatial distribution of Biomphalaria straminea, a potential intermediate host for Schistosoma mansoni, in China

Recherche des facteurs susceptibles d’empêcher la réalisation du cycle deSchistosoma mansonidans les mares de la Grande Terre de Guadeloupe (Antilles françaises)

Contact Info

Product

Resources

About