Intermittent Fasting: Benefits, Side Effects, Quality of Life, and Knowledge of the Saudi Population

Shalabi, Hani; Hassan, Abdulrahman S.; AL-Zahrani, Faris A; Alarbeidi, Abdullah H; Mesawa, Mohammed; Rizk, Hisham; Aljubayri, Abrar A

doi:10.7759/cureus.34722

Cited by 10 publications

(7 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Intermittent Fasting also carried risk of hypoglycemic episodes leading to unconsciousness, vertigo and trembling heartbeat etc. We also found that beneficial effects of intermittent fasting was associated with the marital status, qualification and family history of the patients, while no association was found with gender and age and it is also shown by some other published literature (16,17).…”

Section: Discussionsupporting

confidence: 75%

Role of Intermittent Fasting in the Management of the Diabetes Mellitus Type 2 Patients in Karachi

Shahid,

Shabbir,

Tarrar

et al. 2023

PJMHS

View full text Add to dashboard Cite

To determine the role of intermittent fasting in managing Diabetes Mellitus Type 2 patients in Karachi. Methodology: It was a cross-sectional study conducted at Bahria University Health Sciences Campus, Karachi with total duration of three months from February 2022 to May-2022. After IRB approval random sampling technique was used to recruit subjects. 156 patients with DM type II were part of the study out of which 102 were in fasting among them 75 patients found intermittent fasting beneficial in managing blood glucose and symptoms, remaining 27 did not find it beneficial. Data Analysis was conducted by using SPSS version 25. Results: A total of 156 patients with DM type II were part of the study out of which 102 were fasting among them 75 patients found intermittent fasting beneficial in managing blood glucose and symptoms, remaining 27 did not find it beneficial thus 73.5 % patients were better able to manage DM II with intermittent fasting. There was no association between the beneficial effects of intermittent fasting with a specific type. Conclusion: Intermittent Fasting is beneficial for diabetes mellitus type II patients which proves our alternate hypothesis, but there is no specific type of intermittent fasting associated with it being beneficial. As long as a patient of DM II was observing periods of intermittent fasting, it has been show a clear evident that intermittent fasting plays a key role in the management of diabetes mellitus type II patients. Keywords: Diabetes Mellitus, DM, Intermittent Fasting, Control of DM, Fasting

show abstract

Section: Discussionsupporting

confidence: 75%

Role of Intermittent Fasting in the Management of the Diabetes Mellitus Type 2 Patients in Karachi

Shahid,

Shabbir,

Tarrar

et al. 2023

PJMHS

View full text Add to dashboard Cite

show abstract

“…CCRD showed a positive impact on general health, better energy levels, and fewer role limitations due to physical health compared to TRIF. A study investigating the benefits, side effects, and knowledge of Intermittent Fasting among the Saudi population noted common side effects like headache, lethargy, mood swings, and dizziness [ 30 ]. Therefore, our results support these findings but from the perspective of QoL.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Its Association With Time in Range Among People With Type 2 Diabetes Mellitus Following Different Dietary Interventions: A Crossover Clinical Trial

Deshmane,

Muley

2024

Cureus

View full text Add to dashboard Cite

Background Quality of Life (QoL) is an essential consideration in healthcare. Numerous studies have examined QoL in India; however, data on QoL following different dietary interventions are lacking. Similarly, the use of technology such as continuous glucose monitoring (CGM) for diabetes care has independently demonstrated improvements in glycemic control; however, its association with QoL remains limited. Purpose The purpose was to study the role of different dietary interventions on QoL and its association with Time in Range (TIR), Time Above Range (TAR), and Time Below Range (TBR) among the Type 2 Diabetes Mellitus (T2DM) population. Methodology A crossover interventional clinical trial (CTRI/2022/07/044356) was conducted among participants with T2DM of less than 5 years' duration, aged between 25 and 55 years, with an HbA1c level of less than 8%, and who were on Metformin only. Their QoL was assessed after following two diet patterns: the Continuous Calorie Restricted Diet (CCRD) - calorie reduction with small frequent meals, and Time Restricted Intermittent Fasting (TRIF) - calorie reduction with only two meals a day, using the Modified QoL (MDQOL-17) questionnaire. The association between post-dietary interventions QoL and TIR was studied using a 14-day CGM device. Results The overall QoL of 51 participants at the end of the dietary interventions was significantly better compared to their QoL before any dietary intervention (85.6±19.0% and 63.1±13.0%, respectively, p = 0.000). Decreased TIR correlated with increased role limitations due to physical functioning (p = 0.002) and decreased energy levels (p = 0.00). As TBR increased, role limitation due to emotional well-being increased, and energy levels decreased significantly (p = 0.01). As TAR increased, energy levels decreased (p = 0.01). A simple linear regression model was statistically significant for role limitations due to physical functioning (p = 0.003) and energy fatigue (p = 0.000), suggesting that higher TIR is associated with higher scores in these domains. Conclusion Dietary interventions that improve the TIR and reduce the TAR and TBR can enhance the QoL of individuals with T2DM.

show abstract

“…A study examining 147 individuals with a high BMI following an intermittent fasting regimen revealed common adverse effects, including headache (61.3%), lethargy (68%), mood changes (57.8%), and dizziness and polyuria (55.8 and 46.2%, respectively) ( 37 ). Headache, a prevalent side effect during fasting, is often attributed to hypoglycemia and manifests as a diffuse, non-pulsating headache.…”

Section: Introductionmentioning

confidence: 99%

“…Headache, a prevalent side effect during fasting, is often attributed to hypoglycemia and manifests as a diffuse, non-pulsating headache. It is crucial to acknowledge these potential risks and side effects associated with intermittent fasting to ensure safe and informed implementation of this dietary approach ( 37 , 38 ). On the other hand, various studies have evaluated the benefits of intermittent fasting and have found significant results, including reductions in glucose and insulin levels, as well as notable weight loss and decreased BMI ( 39–41 ).…”

Section: Introductionmentioning

confidence: 99%

The effect of intermittent fasting on microbiota as a therapeutic approach in obesity

Cadena-Ullauri,

Guevara-Ramírez,

Ruiz-Pozo

et al. 2024

Front. Nutr.

View full text Add to dashboard Cite

Obesity, a public health challenge, arises from a complex interplay of factors such as dietary habits and genetic predisposition. Alterations in gut microbiota, characterized by an imbalance between Firmicutes and Bacteroidetes, further exacerbate metabolic dysregulation, promoting inflammation and metabolic disturbances. Intermittent fasting (IF) emerges as a promising dietary strategy showing efficacy in weight management and favoring fat utilization. Studies have used mice as animal models to demonstrate the impact of IF on gut microbiota composition, highlighting enhanced metabolism and reduced inflammation. In humans, preliminary evidence suggests that IF promotes a healthy microbiota profile, with increased richness and abundance of beneficial bacterial strains like Lactobacillus and Akkermansia. However, further clinical trials are necessary to validate these findings and elucidate the long-term effects of IF on microbiota and obesity. Future research should focus on specific tissues and cells, the use of advanced -omics techniques, and exploring the interaction of IF with other dietary patterns, to analyze microbiota composition, gene expression, and potential synergistic effects for enhanced metabolic health. While preliminary evidence supports the potential benefits of IF in obesity management and microbiota regulation, further research with diverse populations and robust methodologies is necessary to understand its implications and optimize personalized dietary interventions. This review explores the potential impact of IF on gut microbiota and its intricate relationship with obesity. Specifically, we will focus on elucidating the underlying mechanisms through which IF affects microbiota composition, as well as its subsequent effects on obesity.

show abstract

Intermittent Fasting: Benefits, Side Effects, Quality of Life, and Knowledge of the Saudi Population

Cited by 10 publications

References 12 publications

Role of Intermittent Fasting in the Management of the Diabetes Mellitus Type 2 Patients in Karachi

Role of Intermittent Fasting in the Management of the Diabetes Mellitus Type 2 Patients in Karachi

Quality of Life and Its Association With Time in Range Among People With Type 2 Diabetes Mellitus Following Different Dietary Interventions: A Crossover Clinical Trial

The effect of intermittent fasting on microbiota as a therapeutic approach in obesity

Contact Info

Product

Resources

About