Internally self-assembled particles entrapped in thermoreversible hydrogels

Lipid Self-Assemblies and Nanostructured Emulsions for Cosmetic Formulations

“…The dispersed system of nanostructured lipid particles (O/W emulsions) exhibits rather low viscosity (milk-like consistency) (Figure 6), which is actually one of the main motivations behind their preparation. Nonetheless, these O/W emulsions can be made viscous, if required, by various means, for instance, by increasing the concentration of the dispersed phase (usually a lipid phase) [94] or by preparing a hydrogel in the continuous phase of these emulsions [125,126] ( Figure 6). The latter can be employed to partially arrest the dynamics of the nanostructured lipid particles [125].…”

Hierarchically Organized Systems Based on Liquid Crystalline Phases

“…ISAsomes entrapped in thermoreversible hydrogels (Guillot et al, 2009b ;Tomsic et al, 2009 ) and their properties are discussed in Section 6.5 . ISAsomes entrapped in thermoreversible hydrogels (Guillot et al, 2009b ;Tomsic et al, 2009 ) and their properties are discussed in Section 6.5 .…”

“…It is possible to increase the viscosity of these dispersions by adding a certain type of hydrogelling agent. Guillot et al (2009b) and Tomsic et al (2009) have performed systematic studies on aqueous systems of the two hydrogelators (KC and MC) and their mixtures for incorporating various ISAsomes. Two different hydrogelling agents, namely, κ -carrageenan (KC) and methylcellulose (MC), (Tomsic et al, 2008 ) have been exploited for this purpose.…”

“…In this section we describe the embedding of ISAsomes in hydrogel networks and their further immobilization by dehydration of the hydrogels to give dry fi lms. Investigations focused on the changes as a function of hydrogelator concentration, type of ISAsome nano- structure (LC phase), and temperature recycling (up and down scans) (Guillot et al, 2009b ;Tomsic et al, 2008Tomsic et al, , 2009. KC is a linear sulfated polysaccharide extracted from red seaweed; whereas MC is a hydrophobically modifi ed form of cellulose that does not occur in nature.…”

“…The ISAsomes stay practically intact, having the same size before and after gelation and dilution (Fig. [Figures (a) and (b) were taken from Tomsic et al (2009) and (c) from Guillot et al (2009b) .] However, the phase behavior of ISAsomes was, in general, only slightly affected by the gel interactions, although it Figure 6.12 Embedding ISAsomes in hydrogels: (a) Thermoreversibility test of the integrity of hexosomes (DU/TC system, δ = 85) as particles during gelation -degelation of 2% MC by DLS.…”