Interobserver Agreement for Confocal Imaging of Ampullary Lesions

Bakhru, Mihir R.; Sethi, Amrita; Jamidar, Priya A.; Singh, Satish K.; Kwon, Richard S.; Siddiqui, Uzma D.; Sawhney, Mandeep S.; Talreja, Jayant P.; Kline, Pamela; Malik, Umer Ejaz; Gaidhane, Monica; Sauer, Bryan G.; Kahaleh, Michel

doi:10.1097/mcg.0b013e3182745f2b

Cited by 11 publications

(4 citation statements)

References 20 publications

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“…Current application for CLE in gastrointestinal (GI) endoscopy includes Barrett's Esophagus, biliary strictures, diagnosis and follow-up of colonic and gastric lesions [92]. Other possible future applications of CLE might also include the diagnosis of breast diseases [93], celiac disease [94], and ampullary lesions [95]. One of the first fields of application of CLE was represented by Barrett's esophagus; the research in this field has greatly contributed to the standardization of confocal image interpretation.…”

Section: Future Perspectives and Role Of Confocal Laser Endomicrosmentioning

confidence: 99%

Serrated Lesions of the Colon-Rectum: A Focus on New Diagnostic Tools and Current Management

Cassese

Amendola

Maione

et al. 2019

Gastroenterology Research and Practice

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Prompt diagnosis and correct management of the so called “serrated lesions” (SLs) of the colon-rectum are generally considered of crucial importance in the past years, mainly due to their histological heterogeneity and peculiar clinical and molecular patterns; sometimes, they are missed at conventional endoscopy and are possibly implicated in the genesis of interval cancers. The aim of this review is to focus on the diagnostic challenges of serrated lesions, underlying the role of both conventional endoscopy and novel technologies. We will show how an accurate and precise diagnosis should immediately prompt the most appropriate therapy other than defining a proper follow-up program. It will be emphasized how novel endoscopic techniques may provide better visualization of mucosal microsurface structures other than enhancing the microvascular architecture, in order to better define and characterize specific patterns of mucosal lesions of the gastrointestinal tract. Standard therapy of SLs of the colon-rectum is still very debated, also due to the relatively lack of studies focusing on treatment issues. The high risk of incomplete resection, together with the high rate of postcolonoscopy interval cancers, suggests the need of an extra care when facing this kind of lesions. Given this background, we will outline useful technical tips and tricks in the resection of SLs, taking aspects such as the size and location of the lesions, as well as novel available techniques and technologies, other than future perspectives, including confocal laser endomicroscopy into consideration. Follow-up of SLs is another hot topic, also considering that their clinical impact has been misunderstood for a long time. The incidence of the so called interval colorectal cancer underlines how some weaknesses exist in current screening and follow-up programs. Considering the lack of wide consensus for the management of some SLs, we will try to summarize and clarify the best strategies for their optimal management.

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Section: Future Perspectives and Role Of Confocal Laser Endomicrosmentioning

confidence: 99%

Serrated Lesions of the Colon-Rectum: A Focus on New Diagnostic Tools and Current Management

Cassese

Amendola

Maione

et al. 2019

Gastroenterology Research and Practice

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“…En lesiones ampulares se ha intentado mejorar la evaluación diagnóstica utilizando pCLE pero con resultados pobres por falta de criterios específicos, y con mala concordancia interobservador, por lo que para esta patología faltan más estudios (41,42).…”

Section: Pólipos Y Cáncer De Colonunclassified

Utilidad de la endomicroscopia confocal láser basada en probes (Cellvizio) en gastroenterología

Piñeros

Cardona

Karia

et al. 2016

Rev. Colomb. Gastroenterol.

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La endomicroscopia confocal láser basada en probes (Cellvizio de Mauna Kea Technologies, París) es una nueva tecnología que permite, durante cualquier procedimiento endoscópico, realizar análisis histológicos en tiempo real (biopsia óptica), mejorando el diagnóstico y ayudando a definir el tratamiento de múltiples patologías digestivas. Es de resaltar, para nuestro medio, su utilidad en patologías de difícil diagnóstico como son las estenosis biliares indeterminadas y las neoplasias quísticas pancreáticas, cuyo diagnóstico temprano y exacto es muy difícil con las técnicas actualmente disponibles, y que es necesario para definir la realización o la exclusión de tratamientos quirúrgicos de alta morbimortalidad y alto costo, como por ejemplo, la cirugía de Whipple. En esta revisión se muestran los aportes actuales de esta tecnología, ya disponible en nuestro medio, para el diagnóstico y estudio de las patologías digestivas.

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“…CLE generates images that elucidate cellular architecture and microvasculature at a level comparable to that achieved with traditional histology [11,12]. In particular, several studies have shown that this technology is useful for determining pathology in a variety of gastrointestinal tissue sites, including Barrett's esophagus [13][14][15], and lesions in the duodenum [16], colonic mucosa [17,18], and pancreatic biliary tract [19][20][21]. Moreover, it has been reported that CLE, incorporated into gastrointestinal endoscopy, is a useful approach for diagnosing various malignancies, including gastric [22,23], esophageal [24,25], colorectal [26,27], and pancreatic cancers [28].…”

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confidence: 97%

A novel approach of optical biopsy using probe-based confocal laser endomicroscopy for peritoneal metastasis

et al. 2015

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Interobserver Agreement for Confocal Imaging of Ampullary Lesions

Cited by 11 publications

References 20 publications

Serrated Lesions of the Colon-Rectum: A Focus on New Diagnostic Tools and Current Management

Serrated Lesions of the Colon-Rectum: A Focus on New Diagnostic Tools and Current Management

Utilidad de la endomicroscopia confocal láser basada en probes (Cellvizio) en gastroenterología

A novel approach of optical biopsy using probe-based confocal laser endomicroscopy for peritoneal metastasis

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