Interobserver Agreement on Clinical Judgment of Work of Breathing in Spontaneously Breathing Children in the Pediatric Intensive Care Unit

Groot, Marcel G. de; Neef, Marjorie de; Otten, M.H.; Woensel, Job B. M. van; Reinout, A.

doi:10.1055/s-0039-1697679

Cited by 5 publications

(3 citation statements)

References 16 publications

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“…As it is considered a predictor of LRTI and patient deterioration, it is helpful for clinical evaluation and decision‐making regarding hospital admission 40,41 . Nevertheless, the parameter is age‐specific, 42 time‐consuming to evaluate, and prone to interobserver variation 38,43 . It has therefore been dichotomized and simplified into the presence or absence of tachypnea for the RSV‐CLASS.…”

Section: Discussionmentioning

confidence: 99%

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RSV‐CLASS —Clinical Assessment Severity Score: An easy‐to‐use clinical disease severity score for respiratory syncytial virus infection in hospitalized children

Gsenger

Bruckner

Ihling

et al. 2023

Journal of Medical Virology

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Respiratory syncytial virus (RSV) is the most common cause of acute respiratory tract infection in infants and young children often leading to severe disease requiring hospitalization. However, validated tools for systematic assessment of disease severity are lacking. This study aimed at creating and validating a standardized, simple-to-use disease severity score for RSV infection in children-the RSV-CLASS (Clinical Assessment Severity Score). Therefore, data from over 700 RSVinfected children over six winter seasons (2014-2020) was analyzed using univariate and multiple regression analyses for the prediction of lower respiratory tract infection (LRTI) as a proxy for a severe course of the disease. Testing a broad range of respiratory symptoms, they eventually yielded seven items. Performing stepwise selection, these were reduced to the final four items: cough, tachypnea, rales, and wheezing, each receiving one point in the proposed score named RSV-CLASS. The score was calculated for children in two cohorts A and B, one for development and one for validation, with an area under the curve of 0.90 and 0.87, respectively. With a score value of 3 or 4, 97.8% and 100% of the children, respectively, were admitted with LRTI and classified correctly. The RSV-CLASS is a disease severity score based on a neutral, analytical approach using prospective data from a large study cohort. It will contribute to systematically assessing the disease severity of RSV infection and can be used for evidence-based clinical decision-making as well as for research settings.

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Section: Discussionmentioning

confidence: 99%

“…40,41 Nevertheless, the parameter is age-specific, 42 timeconsuming to evaluate, and prone to interobserver variation. 38,43 It has therefore been dichotomized and simplified into the presence or absence of tachypnea for the RSV-CLASS.…”

Section: Score Validationmentioning

confidence: 99%

RSV‐CLASS —Clinical Assessment Severity Score: An easy‐to‐use clinical disease severity score for respiratory syncytial virus infection in hospitalized children

Gsenger

Bruckner

Ihling

et al. 2023

Journal of Medical Virology

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“…Offensichtliche Anzeichen einer Dekompensation (vermindertes Bewusstsein, Hypotonie) sind im Allgemeinen erst spät erkennbar und liegen meist kurz vor dem kardiorespiratorischen Kollaps. Erste klinische Anzeichen eines (kompensierten) Versagens sind unzuverlässig und es besteht eine signifikante Variabilität zwischen Beobachtern, insbesondere bei kleinen Kindern [ 28 , 31 , 37 – 45 ].…”

Section: Evidenzen Für Die Leitlinienunclassified

Lebensrettende Maßnahmen bei Kindern (Paediatric Life Support, PLS)

Voorde

Turner

Djakow

et al. 2021

Notfall Rettungsmed

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Die Leitlinien des European Resuscitation Council (ERC) zu den lebensrettenden Maßnahmen bei Kindern (Paediatric Life Support, PLS) basieren auf dem 2020 verfassten „International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations“ der ILCOR (International Liaison Committee on Resuscitation). Dieses Kapitel beinhaltet Leitlinien zur Behandlung kritisch kranker oder verletzter Säuglinge, von Kindern und Jugendlichen vor, während und nach einem Atem-Kreislauf-Stillstand.

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Enhancing Analytical Reasoning in the Intensive Care Unit

Barash

Nanchal

2022

Critical Care Clinics

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Interobserver Agreement on Clinical Judgment of Work of Breathing in Spontaneously Breathing Children in the Pediatric Intensive Care Unit

Cited by 5 publications

References 16 publications

RSV‐CLASS —Clinical Assessment Severity Score: An easy‐to‐use clinical disease severity score for respiratory syncytial virus infection in hospitalized children

RSV‐CLASS —Clinical Assessment Severity Score: An easy‐to‐use clinical disease severity score for respiratory syncytial virus infection in hospitalized children

Lebensrettende Maßnahmen bei Kindern (Paediatric Life Support, PLS)

Enhancing Analytical Reasoning in the Intensive Care Unit

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