Interoceptive Awareness, Decision-Making and Impulsiveness in Male Patients with Alcohol or Opioid Use Disorder

Relationship of Interoceptive Accuracy With Risky Decision-Making and Treatment Outcomes in Male Patients With Alcohol Use Disorder

“…It has been proposed that enhanced HBP is associated with benefits in decisionmaking on the IGT, and this phenomenon relates to the selection of more advantageous options in complex and uncertain situations (Werner et al, 2009). In recent studies that included abstinent in patients with alcohol or opioid use disorder, decreased IAc based on HBP performance was associated with risky decision-making on the IGT (Avcu Meric & Sonmez, 2022;Subay & Sonmez, 2021). The current study investigated whether patients distinguished by low or high IAc levels differed in their IGT performance.…”

“…It has been suggested that IAc is related to both IA and IS and that IAc is the core construct that underpins all other interoceptive measurements (Garfinkel et al, 2015). Recent studies examining IAc based on HBP performance have reported that abstinent patients in different SUD groups (alcohol, opioid, and synthetic cannabinoid use disorder) have similar IAc and their HBP scores are lower than those of healthy controls (Sonmez et al, 2017; Subay & Sonmez, 2021). Additionally, abstinent patients with AUD receive lower HBP scores than healthy control subjects (Ates Col et al, 2016; Avcu Meric & Sonmez, 2022; Jakubczyk et al, 2019, 2021).…”

“…Lower levels of interoceptive perception may be present in individuals with SUD, and damage to the insular cortex caused by substance use may result in a disruption of IA (Verdejo-Garcia et al, 2012). Recent studies have demonstrated that patients with SUD have lower heartbeat perception (HBP) scores on the heart-rate tracking task as an objective physiological performance measure of IAc than healthy control subjects (Ates Col et al, 2016; Avcu Meric & Sonmez, 2022; Hina & Aspell, 2019; Jakubczyk et al, 2019, 2021; Sonmez et al, 2017; Subay & Sonmez, 2021).…”

“…The studies conducted recently by employing Iowa gambling task (IGT) scores as a validated measure of decision-making and HBP scores have underpinned the argument that accurate IAc plays an important role in healthy individual decision-making (Dunn et al, 2010; Werner et al, 2009, 2013). Recent studies have demonstrated that decreased IAc is associated with risky decision-making in abstinent patients with alcohol or opioid use disorder (Avcu Meric & Sonmez, 2022; Subay & Sonmez, 2021).…”

Risky Decision-Making in Adults with Alcohol Use Disorder—A Systematic and Meta-Analytic Review

“…In total, 25 studies indicated that the AUD group showed an aberrant performance (i.e., performed in a riskier fashion) as compared to the CG on one or more of the outcome measures used (25/30 = 83%). Specifically, 20 out of 28 studies (71%) reporting on the total net scores, total financial outcome, or total number of advantageous/disadvantageous choices indicated the overall task performance to be significantly worse (i.e., riskier) in the AUD group as compared to the CG [54,55,64,70,73,76,78,79,82,84,89,90,[92][93][94][95]97,[99][100][101]103]. This increased risk taking corresponds to the medium pooled effect size of 0.56 (95% CI = 0.45-0.68, p < 0.001) that was found in the subgroup meta-analysis for the IGT, which included 27 studies.…”