Establishing loosely coupled collaborations between services provided by autonomous enterprises poses several requirements and challenges for the surrounding service ecosystem. In such context emphasis must be laid especially on the correctness of available metainformation and its usage. Towards this purpose, we characterize service ecosystems by a set of metamodels. The metamodels include domain ontology metamodels defining the vocabulary and knowledge elements needed for collaboration establishment and management, and metamodels relating such domain ontologies with infrastructure services and service production facilities. In this paper we describe the metamodels and discuss their application for interoperability knowledge management.