Interpenetrating hydrogel networks based on polyacrylamide and poly(itaconic acid): synthesis and characterization

Abstract

SUMMARY: The synthesis of sequential and simultaneous semi-interpenetrating hydrogel networks (IPNs) based on polyacrylamide (PAAm) and poly(itaconic acid) (PICA) is described. Polyacrylamide was used as a host polymer. Physical properties of IPN hydrogels were determined by IR, swelling, extraction and density measurements. No indication for the formation of hydrogen-bonded complexation was observed by IR spectroscopy. The extraction results showed that the grafting level between the two components of PAAm/PICA in simultaneous semi-IPN is higher than that observed in sequential IPNS. These results confirm that the decrease in swelling ratios with PICA contents is probably due to the entanglement effect. The properties of IPN hydrogels were found to be dependent on the composition and the type of IPN. Both sequential and simultaneous IPNs have quite different morphologies compared to the pure PAAm host hydrogel.

Polyacrylamide–hydroxyapatite composite: Preparation, characterization and adsorptive features for uranium and thorium

“…The broad and weak bands at 2500-3700 cm À 1 and 1648 cm À 1 were associated with H 2 O [18,24,31]. PAAm was characterized with the main absorptions at 3200-3400 cm À 1 of N-H stretches, at 1640 cm À 1 of amide (C¼O stretching and N-H bending), at 1425 cm À 1 of C-N stretching and at 700 cm À 1 of N-H out-of plane bending [37,38]. PAAm-HAP profile containing all characteristic peaks was the evidence for fine incorporation of inorganic and organic phases within the composite as discussed by Bajpai and Bundela [30].…”

An Investigation into the Influence of Hydrogel Composition on Swelling Behavior and Drug Release from Poly(Acrylamide-co-Itaconic Acid) Hydrogels in Various Media

“…Some research has dealt with hydrogels based on polyacrylamide and itaconic acid or its esters Kayaman et al 1999;Blanco et al 1996Blanco et al , 2003Karadag et al 1996). It was reported that hydrogels of acrylamide and itaconic acid exhibit very high capability to absorb water and have good biocompatibility (Blanco et al 1996;Karadag et al 1996).…”

Semi-Interpenetrating Hydrogel Networks of Poly(2-hydroxyethyl methacrylate) with Poly[(D,L-lactic acid)-co-(ɛ-caprolactam)]

“…These results indicate that the equilibrium swelling ratio, q w , increases slightly with degradation of copolymer component of semi-IPNs. In simultaneous semi-IPN technique, it is found that crosslinking density decreases with the increase of linear polymer content, [32,41] implying that the presence of polyesteramide component restricts the crosslinking of PHEMA network. Hence, it can be concluded that M c of the semi-IPN is higher than pure PHEMA.…”