Abstract:Intertrigo, also known as intertriginous dermatitis, is one of the four separate conditions that fall under the umbrella term of moisture-associated skin damage (MASD). It can affect individuals of all ages. Intertrigo is a common inflammatory skin disorder caused by skin-on-skin friction within skin folds, as a result of moisture becoming trapped because of poor air circulation. It can occur in any area of the body where two skin surfaces are in close contact with each other, such as the axillary, inframammar… Show more
“…Patients are recommended to wear loose, lightweight clothing made from absorbent natural fabrics, while avoiding wool and synthetics fibers. 12 Most of the Thus, the drying of intertriginous areas should focus on the use of agents to reduce sweating, for example, an aluminum acetate solution or zinc oxide antiperspirants, which can be easily applied.…”
Section: Discussionmentioning
confidence: 99%
“…The usual approach to the management of intertrigo is to minimize excessive moisture and friction. Patients are recommended to wear loose, lightweight clothing made from absorbent natural fabrics, while avoiding wool and synthetics fibers 12 . Most of the study cohort preferred loose‐fitting to close‐fitting clothes, yet they still developed intertriginous dermatitis.…”
Background
Intertrigo is an inflammatory skin‐fold condition. Candida infections may occur concurrently or afterward. Topical corticosteroids may reduce inflammation but exacerbate Candida infections. The treatment is contentious.
Objective
To evaluate the efficacies and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin for the treatment of mild‐to‐moderate intertrigo, relative to 1% hydrocortisone cream.
Methods
This randomized, double‐blinded study enrolled 40 intertrigo patients. Twice daily, 20 patients applied adsorbent lotion while the remainder used 1% hydrocortisone cream. Efficacy evaluation, skin biophysical measurements, skin tolerability, safety, and visual analog scale (VAS) patient‐satisfaction scores were evaluated at baseline and Week 2.
Results
The adsorbent lotion showed higher complete cure rates for color, partial epidermal loss, papules/pustules/vesicles/patches, dryness, and scaling than the corticosteroid without statistical significance. Adsorbent lotion demonstrated significantly higher reduction in pruritus than the corticosteroid treatment. Reduction of erythema level using Mexameter and VAS patient‐satisfaction scores were not statistically different between adsorbent lotion and hydrocortisone cream. No adverse effects or superimposed infections were reported.
Conclusions
The anti‐inflammatory efficacies of adsorbent lotion and low‐potency steroid were equivalent. The lotion was safe and produced excellent pruritus reduction. Patient satisfaction was high.
“…Patients are recommended to wear loose, lightweight clothing made from absorbent natural fabrics, while avoiding wool and synthetics fibers. 12 Most of the Thus, the drying of intertriginous areas should focus on the use of agents to reduce sweating, for example, an aluminum acetate solution or zinc oxide antiperspirants, which can be easily applied.…”
Section: Discussionmentioning
confidence: 99%
“…The usual approach to the management of intertrigo is to minimize excessive moisture and friction. Patients are recommended to wear loose, lightweight clothing made from absorbent natural fabrics, while avoiding wool and synthetics fibers 12 . Most of the study cohort preferred loose‐fitting to close‐fitting clothes, yet they still developed intertriginous dermatitis.…”
Background
Intertrigo is an inflammatory skin‐fold condition. Candida infections may occur concurrently or afterward. Topical corticosteroids may reduce inflammation but exacerbate Candida infections. The treatment is contentious.
Objective
To evaluate the efficacies and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin for the treatment of mild‐to‐moderate intertrigo, relative to 1% hydrocortisone cream.
Methods
This randomized, double‐blinded study enrolled 40 intertrigo patients. Twice daily, 20 patients applied adsorbent lotion while the remainder used 1% hydrocortisone cream. Efficacy evaluation, skin biophysical measurements, skin tolerability, safety, and visual analog scale (VAS) patient‐satisfaction scores were evaluated at baseline and Week 2.
Results
The adsorbent lotion showed higher complete cure rates for color, partial epidermal loss, papules/pustules/vesicles/patches, dryness, and scaling than the corticosteroid without statistical significance. Adsorbent lotion demonstrated significantly higher reduction in pruritus than the corticosteroid treatment. Reduction of erythema level using Mexameter and VAS patient‐satisfaction scores were not statistically different between adsorbent lotion and hydrocortisone cream. No adverse effects or superimposed infections were reported.
Conclusions
The anti‐inflammatory efficacies of adsorbent lotion and low‐potency steroid were equivalent. The lotion was safe and produced excellent pruritus reduction. Patient satisfaction was high.
“…The management of intertrigo and associated infections is summarised in Table 3. 11,12 Superficial Fungal Infections…”
Section: Intertrigomentioning
confidence: 99%
“…The management of intertrigo and associated infections is summarised in Table 3. 11,12 Figure 1.Left fourth toe web intertrigo with superimposed tinea pedis (interdigital macerated type).…”
Skin disorders among individuals receiving palliative care may be associated with the primary condition or underlying comorbidities and patients may experience pruritus, discomfort or pain. Common conditions include xerosis, pressure ulcers, intertrigo, superficial fungal infections, telogen effluvium, pruritus, herpes zoster, eczematous disorders and edema. During end-of-life care, there is reduced skin perfusion and metabolism hence leading to susceptibility to infection, pressure and injury. Other factors affecting the skin include limited mobility, nutritional deficits and immunosuppression. Although treatment strategies for each skin condition are usually aligned with standard protocols, considerations among these patients include limited life-expectancies, potential treatment burden, drug-drug interactions as well as comfort-directed rather than cure-directed therapy. For patients with xerosis cutis, the regular use of moisturisers is recommended. The management and prevention of pressure ulcers include the strategies of skin assessment and care, pressure redistribution, nutrition and hydration and ulcer care. Superficial fungal infections require treatment with appropriate topical and/or systemic antifungals while antivirals and adjunctive treatment can be prescribed for herpes zoster. Treatment and symptom control of skin disorders in this population can improve quality of life and patients’ comfort level.
“…A groin incision is commonly used in vascular surgery to expose the femoral vessels and is used for many frequently performed procedures. 1 , 2 Given the groin's proximity to the external genitalia and anal canal, skin flora and predisposition to intertrigo (particularly in obese patients) 3 ; it is unsurprising that groin wound surgical site infections (SSIs) are commonly experienced by vascular surgery patients—a population with a high prevalence of risk factors for nosocomial infection such as diabetes and smoking. 1 , 2 …”
The objectives were to determine the surgical site infection incidence (including superficial/deep) fter arterial intervention through non‐infected groin incisions and identify variables associated with incidence. MEDLINE, EMBASE and CENTRAL databases were searched for randomised controlled trials and observational studies of adults undergoing arterial intervention through a groin incision and reported surgical site infection. Infection incidence was examined in subgroups, variables were subjected to meta‐regression. One hundred seventeen studies reporting 65 138 groin incisions in 42 347 patients were included. Overall surgical site infection incidence per incision was 8.1% (1730/21 431): 6.3% (804/12 786) were superficial and 1.9% (241/12 863) were deep. Superficial infection incidence was higher in randomised controlled trials (15.8% [278/1762]) compared with observational studies (4.8% [526/11 024]); deep infection incidence was similar (1.7% (30/1762) and 1.9% (211/11 101) respectively). Aneurysmal pathology (
β
= −10.229,
P
< .001) and retrospective observational design (
β
= −1.118,
P
= .002) were associated with lower infection incidence. Surgical site infection being a primary outcome was associated with a higher incidence of surgical site infections (
β
= 3.429,
P
= .017). The three‐fold higher incidence of superficial surgical site infection reported in randomised controlled trials may be because of a more robust clinical review of patients. These results should be considered when benchmarking practice and could inform future trial design.
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