Intervention recommendations and subsequent access to services following clinical assessment for fetal alcohol spectrum disorders

Pei, Jacqueline; Baugh, Lauren; Andrew, Gail; Rasmussen, Carmen

doi:10.1016/j.ridd.2016.11.007

Cited by 15 publications

(8 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These awareness programs are carried out as part of the general social work services rendered to the people in the community. In general, these awareness programs focus on drug and substance use/abuse suggesting that preventive efforts for FASD may not necessarily require specialized programs [48,49]. However, there are few prevention programs targeting women and pregnant women [15,16] at clinics with the aim of preventing FASD.…”

Section: Discussionmentioning

confidence: 99%

Policymakers’ Perspectives Towards Developing a Guideline to Inform Policy on Fetal Alcohol Spectrum Disorder: A Qualitative Study

Adebiyi

Mukumbang

Cloete

et al. 2019

IJERPH

View full text Add to dashboard Cite

Fetal alcohol spectrum disorder (FASD) has a high prevalence in South Africa, especially among the poor socioeconomic communities. However, there is no specific policy to address FASD. Using a qualitative study design, we explored the perspectives of policymakers on guidelines/policies for FASD, current practices and interventions, and what practices and interventions could be included in a policy for FASD. The data analysis was done using the Framework Method. Applying a working analytical framework to the data, we found that there is no specific policy for FASD in South Africa, however, clauses of FASD policy exist in other policy documents. Preventive services for women and screening, identification, assessment, and support for children are some of the current practices. Nevertheless, a multi-sectoral collaboration and streamlined program for the prevention and management of FASD are aspects that should be included in the policy. While there are generic clauses in existing relevant policy documents, which could be attributed to the prevention and management of FASD, these clauses have not been effective in preventing and managing the disorder. Therefore, a specific policy to foster a holistic and coordinated approach to prevent and manage FASD needs to be developed.

show abstract

Section: Discussionmentioning

confidence: 99%

Policymakers’ Perspectives Towards Developing a Guideline to Inform Policy on Fetal Alcohol Spectrum Disorder: A Qualitative Study

Adebiyi

Mukumbang

Cloete

et al. 2019

IJERPH

View full text Add to dashboard Cite

show abstract

“…We also discovered that there are only few management services targeting adults with FASD [ 60 ]. Our study highlights the need for a specialized intervention, which will enable children with FASD to receive early intervention and follow-up to adulthood [ 61 , 62 ]. Early interventions show promising outcomes and have the ability to prevent secondary disabilities.…”

Section: Discussionmentioning

confidence: 99%

Exploring service providers’ perspectives on the prevention and management of fetal alcohol spectrum disorders in South Africa: a qualitative study

et al. 2018

View full text Add to dashboard Cite

BackgroundFetal alcohol spectrum disorder (FASD) is among the leading causes of developmental and intellectual disabilities in individuals. Although efforts are being made toward the prevention and management of FASD in South Africa, the prevalence remains high. The sustained high prevalence could be attributed to several factors, including the lack of policy for a coordinated effort to prevent, diagnose and manage FASD nationally. In this study, our aim was to explore the perspectives of service providers (health and allied professionals, teachers, social workers) on the prevention and management of FASD towards developing a guideline to inform policy.MethodGuided by the exploratory qualitative research design, we purposively sampled relevant service providers in the field of FASD prevention and management for focus group discussions. Nine of these discussions were conducted with to eight participants per discussion session. The discussants were asked various questions on the current and required interventions and practices for the prevention and management of FASD. Following the Framework Method, data were transcribed verbatim and analysed using the thematic content analysis approach.ResultsOur findings show that aspects of the prevention and management of alcohol-related conditions are present in various policies. However, there is no clear focus on coordinated, multi-sectoral efforts for a more comprehensive approach to the prevention and management of FASD. The participants recognized the need for specific requirements on broad-based preventive awareness programs, training and support for parents and caregivers, inclusive education in mainstream schools and training of relevant professionals.ConclusionComprehensive and coordinated prevention and management programs guided by a specific policy could improve the prevention and management of FASD. Policy formulation demonstrates commitment from the government, highlights the importance of the condition, and elaborates on context-specific prevention and management protocols.Electronic supplementary materialThe online version of this article (10.1186/s12889-018-6126-x) contains supplementary material, which is available to authorized users.

show abstract

“…Alcohol consumption has several pathological effects, such as dysregulation of the neuroimmune system, neurotransmitter disorders, or epigenetic modifications [ 72 ]; however, oxidative stress damage is considered one of the primary causes of alcohol keratogenesis [ 73 ]. Although early therapies, such as developmental therapy or behavioral interventions, may prevent some specific disorders and secondary disabilities [ 74 , 75 ], there are no specific treatments for alcohol-related alterations, and FASD phenotypes persist for a lifetime. Pharmacotherapy for the treatment of specific cognitive and behavioral traits that share a common framework with other neurological disorders has been tested.…”

Section: Resultsmentioning

confidence: 99%

Therapeutic Effects of Catechins in Less Common Neurological and Neurodegenerative Disorders

et al. 2021

View full text Add to dashboard Cite

In recent years, neurological and neurodegenerative disorders research has focused on altered molecular mechanisms in search of potential pharmacological targets, e.g., imbalances in mechanisms of response to oxidative stress, inflammation, apoptosis, autophagy, proliferation, differentiation, migration, and neuronal plasticity, which occur in less common neurological and neurodegenerative pathologies (Huntington disease, multiple sclerosis, fetal alcohol spectrum disorders, and Down syndrome). Here, we assess the effects of different catechins (particularly of epigalocatechin-3-gallate, EGCG) on these disorders, as well as their use in attenuating age-related cognitive decline in healthy individuals. Antioxidant and free radical scavenging properties of EGCG -due to their phenolic hydroxyl groups-, as well as its immunomodulatory, neuritogenic, and autophagic characteristics, makes this catechin a promising tool against neuroinflammation and microglia activation, common in these pathologies. Although EGCG promotes the inhibition of protein aggregation in experimental Huntington disease studies and improves the clinical severity in multiple sclerosis in animal models, its efficacy in humans remains controversial. EGCG may normalize DYRK1A (involved in neural plasticity) overproduction in Down syndrome, improving behavioral and neural phenotypes. In neurological pathologies caused by environmental agents, such as FASD, EGCG enhances antioxidant defense and regulates placental angiogenesis and neurodevelopmental processes. As demonstrated in animal models, catechins attenuate age-related cognitive decline, which results in improvements in long-term outcomes and working memory, reduction of hippocampal neuroinflammation, and enhancement of neuronal plasticity; however, further studies are needed. Catechins are valuable compounds for treating and preventing certain neurodegenerative and neurological diseases of genetic and environmental origin. However, the use of different doses of green tea extracts and EGCG makes it difficult to reach consistent conclusions for different populations.

show abstract

Intervention recommendations and subsequent access to services following clinical assessment for fetal alcohol spectrum disorders

Cited by 15 publications

References 21 publications

Policymakers’ Perspectives Towards Developing a Guideline to Inform Policy on Fetal Alcohol Spectrum Disorder: A Qualitative Study

Policymakers’ Perspectives Towards Developing a Guideline to Inform Policy on Fetal Alcohol Spectrum Disorder: A Qualitative Study

Exploring service providers’ perspectives on the prevention and management of fetal alcohol spectrum disorders in South Africa: a qualitative study

Therapeutic Effects of Catechins in Less Common Neurological and Neurodegenerative Disorders

Contact Info

Product

Resources

About