Interventions for frostbite injuries

Lorentzen, Anne Kathrine; Davis, Christopher; Penninga, Luit

doi:10.1002/14651858.cd012980

Cited by 6 publications

(3 citation statements)

References 29 publications

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“…If the affected tissue spontaneously rewarms, the patient should remain in a warm area to prevent refreezing, as this can cause additional reperfusion injury. 16,17 Once stabilized, patients should be transported to the nearest medical facility.…”

Section: Classification Of Frostbitementioning

confidence: 99%

Practical Review of the Current Management of Frostbite Injuries

Zaramo

Green

Janis

2022

Plastic and Reconstructive Surgery - Global Open

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Summary: Frostbite is an injury that occurs when the skin and tissues are exposed to temperatures below their freezing point. This type of injury can lead to various complications such as functional loss, chronic pain, and psychological trauma. As such, understanding frostbite management is crucial for optimal patient care. A scoping review was conducted in February 2022 using PubMed, EMBASE, referenced articles and snowballing to identify relevant published articled using the terms “frostbite” and “management” and “surgery. Articles related to pathophysiology, classifications, radiography, complications, and medical and surgical management were included to formulate recommendations for practical management. Two hundred fifty-one articles were identified and 54 met inclusion criteria. Rapid rewarming in warm water (40-42 °C) remains the standard of care. Thrombolytic therapy has been shown in numerous studies to improve tissue salvage. Radiographic imaging has become crucial in the evaluation and management in frostbite injury. Current literature recommends delayed surgery with soft tissue debridement and bone scan-guided amputations. Surgical intervention including debridement, selective blister drainage, fasciotomies, surgical salvage, skin grafts‚ and flaps are often necessary in these patients towards optimizing form and function. The true prevalence and incidence of frostbite injury is unknown. A centralized national database will improve our understanding of the diagnostic and management modalities used in frostbite care. Plastic surgeons have a critical role in the management of frostbite care and must work with an interdisciplinary team to identify the best treatment route for optimal patient care.

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Section: Classification Of Frostbitementioning

confidence: 99%

Practical Review of the Current Management of Frostbite Injuries

Zaramo

Green

Janis

2022

Plastic and Reconstructive Surgery - Global Open

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“…Of note, during the first 24 h, the transfer of patients to a facility capable of administering thrombolysis, and, during the first 72 h, hospital admission for iloprost treatment, should be considered. Healing of frostbite can take from a few days up to several months and in some instances amputation of nonviable tissue is necessary [43,44]. For the management of frostbite long-term sequelae, Botulinum toxin has been proposed as a treatment for neuropathic and vasomotor difficulties [45].…”

Section: Managementmentioning

confidence: 99%

Long-Term Sequelae of Frostbite—A Scoping Review

Regli

Strapazzon

Falla

et al. 2021

IJERPH

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Frostbite is tissue damage caused by freezing temperatures and constitutes an important cause of morbidity in cold climate zones and high altitude. The direct effects of sub-zero temperatures lead to tissue freezing, electrolyte shifts and pH alterations, microvascular damage, and eventually to cell death. Upon rewarming, inflammatory reperfusion injury and thrombosis may lead to further tissue damage. Several studies and various case reports show that many patients suffer from long-term sequelae such as vasomotor disturbances (associated with susceptibility to refreezing), and neuropathic and nociceptive pain, as well as damage to skeletal structures. There are still many uncertainties regarding the pathophysiology of these sequelae. It has been shown that the transient receptor potential channel (TRP) family plays a role in cold allodynia. Botulinum Toxin type A (BTX-A) injections have been reported to be beneficial in vasomotor and neuropathic disturbances secondary to frostbite. Epidural sympathetic block has been used for short-term treatment of frostbite induced chronic pain. Furthermore, amitriptyline, gabapentinoids, and duloxetine may have some benefits. Frostbite arthritis clinically resembles regular osteoarthritis. In children there is a risk of epiphyseal cartilage damage leading to bone deformities. Despite some promising therapeutic concepts, the scarcity of data on frostbite long-term sequelae in the literature indicates the need of more in-depth studies of this pathology in all its aspects.

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“…Barbaloin is very much useful in the treatment of frostbite due to their anti-inflammatory effects. Barbaloin can effectively support and may helpful in the process of tissue healing and also it can make new cells that are healthy by nature or good to treat frostbite symptoms in a more speedy and effective way [43].…”

Section: Frostbitementioning

confidence: 99%

Traditional and medicinal use of Barbaloin: potential for the management of various diseases

Singh

Goyal²,

Sondhi

et al. 2020

joapr

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Barbaloin is the phytoconstituent which is obtained from the plant known as aloe vera. As we all know aloe vera is the main curative medicinal plants, has been traditionally used as alternative treatment against the many skin diseases. Barbaloin extracted from the aloe vera plant which is physically light yellow colored powder. Extraction of barbaloin from the plant Aloe barbadensis Miller had been accomplished by the Soxhelt extraction, Batch extraction experiment and Ultrasound assisted extraction method (UAE). Barbaloin showed various kinds of therapeutic and medicinal properties like anti-diabetic, antioxidants, anti-cancer, anti-inflammatory and and anti-microbial. It also has good effect on cardiovascular system, test perception, enzyme or metabolism and bioavailability. Our Skin plays an important role in the development of skin diseases because there are many types of skin disorders are developed and the variety of disorders may result to dermatitis or they affect the social wellbeing of a person. Due to their good pharmacological activities, Barbaloin have great potential to treat the different type of skin disorders like Eczema, Psoriasis, Burns and wound, Acne, Dandruff, Frostbite, Rashes, Cold sores, Razor burn and Sunburn. To access the effective use of barbaloin there are various attempts have been experimented on the subject of their Pharmacological activities to check their effect on skin disease and the steps regarding the Isolation of barbaloin also has been made. We can examine their effects on chronic skin diseases. In this review article we discuss about the potential of barbaloin on skin disorders, medicinal importance or Pharmacological activities and their methods of extraction.

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Interventions for frostbite injuries

Cited by 6 publications

References 29 publications

Practical Review of the Current Management of Frostbite Injuries

Practical Review of the Current Management of Frostbite Injuries

Long-Term Sequelae of Frostbite—A Scoping Review

Traditional and medicinal use of Barbaloin: potential for the management of various diseases

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