“…From the 45 studies selected, we excluded 27 studies (Figure 2): 15 studies were not focused on DAES (Graser, 1984;Schou et al, 1989;Weitz et al, 1992;Salonen et al, 1996;Naert et al, 1999;Seoane et al, 1999;Frenkel et al, 2001;Lo Muzio et al, 2001;García-Pola Vallejo et al, 2002;Simons et al, 2002;Peroz et al, 2003;Pearson et al, 2007;Silva-Lovato et al, 2010;Srinivasan and Gulabani, 2010;Nissan et al, 2011), one was a protocol of a systematic review (Hugo et al, 2005), five were in vitro studies (Budtz-Jörgensen, 1977;Mähönen et al, 1998;Ebadian et al, 2008;Ferreira et al, 2009;Redding et al, 2009) and six other studies (Hedegard, 1976;Felber and Gasser, 1983;Carlino et al, 1992;Emami et al, 2008;Simunović-Soskić et al, 2010) including a duplicated one (Cross et al, 2000a,b).…”