Intestinal bacterial flora and bile salt studies in hypogammaglobulinaemia

Abstract

SUMMARY Five patients with adult acquired hypogammaglobulinaemia, four of whom were achlorhydric, were studied. Jejunal bacterial counts were much higher than those in a control group of acid secretors, but were similar to those in a control group of patients with pernicious anaemia; Giardia lamblia were isolated from the jejunal content of all patients with hypogammaglobulinaemia.

Jejunal microflora in malnourished Gambian children.

“…coli, bacteroides, and klebsiellas (Strauss, Donaldson, and Gardner, 1961), or possibly by the production of unconjugated bile acids (Dawson and Isselbacher, 1960) and the inability to absorb fat (Tebaqchali and Booth, 1967 (Ironside, Tuxford, and Heyworth, 1970 (James, 1968 (Parkin et al, 1972) with slight modifications. Within 5 minutes of the specimens being aspirated, 0 -1 ml jejunal fluid was placed into 0 9 ml glucose broth, using a micropipette and the contents were mixed.…”

Mucosal secretory IgA and secretory piece in adult coeliac disease

“…Received for publication 3 July 1973. McClelland, O'Moore, Percy-Robb, Grant, and Shearman, 1972), and dietary constituents (Davis, Bierman, Pierson, Maas, and Iannetta, 1970;Ferguson and Carswell, 1972).…”

Bacterial agglutination studies with secretory IgA prepared from human gastrointestinal secretions and colostrum

“…The finding of this range of activity in intestinal samples supports the view that the normal production of antibacterial antibody may have a role in the homeostasis of the gut flora. In hypogammaglobulinaemia the pattern of colonization of the intestine may be abnormal even though the total numbers of organisms may not be significantly different from the numbers in control patients (Parkin, McClelland, O'Moore, Percy-Robb, Grant, and Shearman, 1972).…”