2022
DOI: 10.3389/fcimb.2021.807462
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Intestinal Immune System and Amplification of Mouse Mammary Tumor Virus

Abstract: Mouse mammary tumor virus (MMTV) is a virus that induces breast cancer in mice. During lactation, MMTV can transmit from mother to offspring through milk, and Peyer’s patches (PPs) in mouse intestine are the first and specific target organ. MMTV can be transported into PPs by microfold cells and then activate antigen-presenting cells (APCs) by directly binding with Toll-like receptors (TLRs) whereas infect them through mouse transferrin receptor 1 (mTfR1). After being endocytosed, MMTV is reversely transcribed… Show more

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Cited by 3 publications
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References 85 publications
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