Intestinal microbiota and lipid metabolism responses in the common carp (Cyprinus carpio L.) following copper exposure

Meng, Xiaolin; Li, Shuai; Qin, Chaobin; Zhu, Zhenxin; Hu, Wenpan; Yang, Liping; Lu, Rongzhu; Li, Wenjun; Nie, Guoxing

doi:10.1016/j.ecoenv.2018.05.050

Cited by 152 publications

(63 citation statements)

References 38 publications

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“…Analysis of the literature on accumulation of the studied metals proves that many microorganisms are able to sorb these elements in large quantities, for example, a strain of Z. ramigera is able to accumulate up to 170 mg of copper at 1 g of dry biomass, and cadmium ions up to 16.3 mg/g [7].…”

Section: Resultsmentioning

confidence: 99%

A study on heavy metal sorption properties of intestinal microbiota in vitro

Sizentsov

Кван

et al. 2019

E3S Web Conf.

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Water and soil pollution by heavy metals has led to their accumulation in the ground and waters, to a sharp decline of ecosystem biopotential, and to foodstuff contamination, resulting in internal pollutions in bodies of humans and animals with food, air, water. In this regard, the purpose of our study was to examine the impact of heavy metals on the growth of representatives of rats’ intestinal microbiota and to estimate sorption characteristics of these microorganisms. The research was conducted in three stages: i) a study of essential and xenobiotic elements’ biotoxicity; ii) their impact on the growth of the microbiota in periodic cultivation; and iii) studying bioaccumulative characteristics. In the research, we discovered that all investigated organisms had pronounced resistance to lead and iron, which was confirmed by the results of the evaluating the impact on the growth and the accumulating characteristics of the studied microorganisms (more than 50%). The strain of E. faecium has the most pronounced sorption characteristics – its level of accumulation amounted for iron –63.3%, lead – 61%, zinc – 38.4%, copper – 11.4%, and cadmium – 33.2%, minimum values were obtained in samples of L. acidophilus, which sorbed these elements in concentrations of 46.2%, 42.3%, 10.3%, 3.8%, and 5.3%, respectively.

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Section: Resultsmentioning

confidence: 99%

A study on heavy metal sorption properties of intestinal microbiota in vitro

Sizentsov

Кван

et al. 2019

E3S Web Conf.

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“…Such behavior impairment by copper seems to affect the nervous system of the fish [114]. Other studies in Cyprinus carpio show that low copper concentrations also affect the microbiota diversity and lipid metabolism [110].…”

Section: Effect Of Heavy Metalsmentioning

confidence: 88%

“…Previous studies have demonstrated that environmental pollutants affect the gut microbiota even at low concentration [109]. The metagenomic analyses of the gut microbiota from Cyprinus carpio have made evident the prevalence (or selection) of bacterial genera containing genes associated to metal resistance as well as genes involved in heavy metal biotransformation pathways that tend to attenuate their toxicity in fishes exposed to heavy metals [110,111].…”

Section: Effect Of Heavy Metalsmentioning

confidence: 99%

Application of Metagenomics to Chilean Aquaculture

Tello¹,

Valdés²,

Vargas³

et al. 2020

Metagenomics - Basics, Methods and Applications

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Aquaculture is a rapidly expanding food production sector, facing the challenge of growth both increasing its efficiency and reducing its negative impact on the environment. Metagenomics is an emerging tool in aquaculture that helps to understand the complex host (fish-shellfish)-microbiota-pathogen-environment relationship underlying disease outbreaks, monitoring the dynamics of microbial diversity in farmed animals subject to different environmental conditions or perturbations. As Chile takes an important share of world aquaculture market, this chapter reviews the actual and potential applications of metagenomics to support a sustainable expansion and diversification of Chilean aquaculture. The focus is on (i) the role and function of the gut microbiota in the proper immunostimulation and disease control and (ii) the role of metagenomics in monitoring environmental microbial biodiversity and dynamics in relation to disease persistence and ecosystem stability. We conclude that despite the importance of the aquaculture sector in Chile, the application of metagenomics to deal with disease control and ecosystem preservation is still an emerging field of study. Understanding host (fish-shellfish)microbiota-pathogen-environment diversity of interactions in a more holistic view, i.e., the holobiome approach, could be key to develop rational strategies to improve productivity by increasing resistance to diseases and reducing the use of antibiotics and their negative environmental impact.

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“…Environmental pollutants affect the fish's health by influencing various metabolic pathways, especially on the food intake and the subsequent energy transformation, and finally induce host obesity [61,62]. Thus, the alteration of gut microbiota exposed to environmental challenges is always related to the diseases in the host or the metabolic functions [63,64].…”

Section: Discussionmentioning

confidence: 99%

DEHP chronic exposure disturbs the gut microbial community and metabolic homeostasis: Gender-based differences in zebrafish

Pei

Jia

Xin

et al. 2020

Preprint

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Background: Di-(2-ethylhexyl) phthalate (DEHP), a predominant phthalate ester (PAE), exhibits various toxic potentials with environmental and human health risks. However, the chronic effects of DEHP exposure on gut microbiota and associated host’s health are still largely unexplored. Here, zebrafish were exposed to relative environmental levels (0-100 μg/L) of DEHP from embryos to adult (3.5 months), then the developmental indexes and microbiota as well as the related energy metabolites in gut tissues were checked to unveil the effects during the growth progress. Results: The results indicated that the composition of gut microbiota was different among male and female adult zebrafish, and DEHP disrupted the diversity and richness of the bacterial community. The histopathological analysis of intestinal tissues revealed the decrease of villus length and tunica muscularis thickness, especially the goblet cells per villi in male fish. Moreover, energy metabolites in gut tissues were actively increased at lower levels groups, which probably contribute to the condition factor of host. For immune-related genes, the expression levels of il-8 was increased both in female and male fish in the lowest concentration (10 μg/L), but the tlr-5 and il-1β genes were in the different response with significantly decreased in female fish. Conclusion: Taken all together, those results indicated that chronic exposure to DEHP led to zebrafish obesity with the disturbed bacterial community in the gut and related metabolism pathways. Those findings provided deep insights on the perturbation of gut microbiota, metabolic homeostasis, and gender-based differences by DEHP exposure.

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Intestinal microbiota and lipid metabolism responses in the common carp (Cyprinus carpio L.) following copper exposure

Cited by 152 publications

References 38 publications

A study on heavy metal sorption properties of intestinal microbiota in vitro

A study on heavy metal sorption properties of intestinal microbiota in vitro

Application of Metagenomics to Chilean Aquaculture

DEHP chronic exposure disturbs the gut microbial community and metabolic homeostasis: Gender-based differences in zebrafish

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