Intestinal Mucositis Induced by 5- Fluorouracil and the Possible Protective Effect of Probiotics Containing Lactobacillus in Adult Male Albino Rats: Histological and Immunohistochemical Study
Abstract:Introduction:Intestinal mucositis is the most prevalent side effect of antineoplastic drug 5-flurouoracil (5-FU). Probiotics are live microorganisms that improve intestinal immune regulation. So, probiotics might have a beneficial effect to reduce the chemotherapy-induced enterotoxicity. Aim: This study aimed to assess mucositis induced by 5-FU and the possible protective effect of probiotics. Methods: 50 healthy albino adult male rats were divided into five equivalent groups. Control group, probiotic group wa… Show more
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