“…The majority of studies found significant positive associations between ACEs and problematic adult drinking behavior ( N = 35), but several studies reported mixed effects ( N = 13), and eleven studies did not find significant associations (Agorastos et al, 2014; Carlson, Oshri, & Kwon, 2015; Horan & Widom, 2015; Hostinar, Lachman, Mroczek, Seeman, & Miller, 2015; Klanecky, McChargue, & Bruggeman, 2012; Klanecky, Woolman, & Becker, 2015; Nikulina, Widom, & Brzustowicz, 2012; Salem et al, 2013; Tyler, Schmitz, & Adams, 2015; Ulibarri, Ulloa, & Salazar, 2015; Ullman & Sigurvinsdottir, 2015). For example, summary adversity scores were not associated with problematic alcohol-related behaviors in multiple study populations, including the MIDUS II Study (Hostinar et al, 2015), male Marines (Agorastos et al, 2014), some samples of college students (Carlson, Oshri, et al, 2015; Goldstein et al, 2010; Klanecky et al, 2012; Klanecky et al, 2015), urban lesbian, gay or bisexual (LGB) AI/AN (Yuan et al, 2014), and recently paroled men (Salem et al, 2013).…”