Intra-individual comparison after combined phaco-trabecular aspiration in pairs of pseudoexfoliative eyes

Rosentreter, André; Dinslage, Sven; Dietlein, Thomas S.

doi:10.1007/s00417-009-1174-7

Cited by 10 publications

(12 citation statements)

References 17 publications

(19 reference statements)

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“…Gillmann et al determined considerable outcome predictability for the second eye based on the outcome after XEN45 Gel Stent implantation (Allergan, Dublin, California) in the first eye 2 . Similar observations were also made by Rosentreter et al in patients bilaterally treated with cataract surgery combined with trabecular aspiration 3 …”

Section: Introductionsupporting

confidence: 87%

Predictability of ab‐interno trabeculectomy success in the subsequent eye: A contralateral eye comparison study

Kiessling

Rennings

Hild

et al. 2021

Clinical Exper Ophthalmology

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Background To determine whether the outcome of the first eye may serve as a predictor for intraocular pressure (IOP)‐lowering effectiveness in the second eye following bilateral ab interno trabeculectomy. Methods This retrospective single‐centre study included 168 eyes from 84 participants, who underwent combined Trabectome surgery with phacoemulsification cataract surgery in a hospital setting. The clinical endpoint was defined as either ‘success’ or ‘failure’ based on four separate scores at the longest follow‐up time point: IOP at follow‐up <21 mm Hg (Score A) or IOP < 18 mm Hg (Score B), without re‐surgery and IOP reduction >20%; IOP ≤15 mm Hg without re‐surgery and IOP reduction ≥40% (Score C); and the sole absence of re‐surgery according to the discretion of the surgeon (Score D). Results No significant difference was observed between the outcomes of first and second eyes. The frequency of success in the second eye after effective surgery in the first eye significantly exceeded that after prior failure. Within our analysis, the probability calculations determined a 75% chance of success following prior success for Score A. If surgery in the first eye failed, the chance of success in the subsequent eye was 37%. The corresponding probabilities were 79% and 32% for Score B, 56% and 9% for Score C, and 99% and 50% for Score D. Conclusion The results of our study offer a useful tool to assess the success of subsequent eye surgeries based on the outcome in the initial eye, owing to the high predictive potential.

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Section: Introductionsupporting

confidence: 87%

Predictability of ab‐interno trabeculectomy success in the subsequent eye: A contralateral eye comparison study

Kiessling

Rennings

Hild

et al. 2021

Clinical Exper Ophthalmology

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“…Pre- and postoperative antiglaucomatous medication was classified according to a medication score [17]. Surgical (absolute) success was defined as an IOP of 18 mm Hg or lower and a relative decrease of 20% or more compared to the preoperative IOP, without any additional glaucoma surgery or medication.…”

Section: Design and Methodsmentioning

confidence: 99%

Trabeculectomy Using Mitomycin C versus an Atelocollagen Implant: Clinical Results of a Randomized Trial and Histopathologic Findings

et al. 2013

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Purpose: To assess the efficacy of trabeculectomy with a biodegradable Ologen™ implant (OLO) versus mitomycin C (MMC) in patients in a prospective randomized clinical trial. Methods: In the MMC group (15 patients), trabeculectomy was performed according to standard protocols. In the OLO group (15 patients) after standard trabeculectomy, the implant was positioned on top of the scleral flap, and no MMC was applied. Results: Mean preoperative intraocular pressure (IOP) levels (OLO: 28.0 ± 9.4; MMC: 23.9 ± 5.0 mm Hg; p = 0.21) and medication score (OLO: 3.4 ± 1.6; MMC: 3.6 ± 1.5; p = 0.56) were comparable in both groups. One year after surgery, the mean IOP was 15.9 ± 4.5 mm Hg in the OLO group (p < 0.01, 43% reduction) and 11.0 ± 2.6 mm Hg in the MMC group (p < 0.01, 54% reduction). The surgical success rate 12 months after surgery was 93.3% in the MMC group and 40% in the OLO group (p = 0.01). Conclusions: With the atelocollagen-glycosaminoglycan matrix OLO it was not possible to reach the surgical success rate and pressure reduction achieved in the MMC group.

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“…Only a few studies have described the outcomes of the fellow eye after glaucoma surgery. Predictive values for trabecular aspiration and trabectome surgery have been reported [ 15 , 16 ]. Upon filtering surgery investigations, Mietz et al showed similar trends in the success rate of fellow eyes after trabeculectomy [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

Predictability of success and open conjunctival revision rates in the subsequent eye after XEN45 Gel Stent implantation according to lens status

Kiessling¹,

Rennings²,

Hild³

et al. 2022

Graefes Arch Clin Exp Ophthalmol

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Purpose To determine the predictability of success and the risk of open conjunctival revision in the subsequent eye after XEN45 Gel Stent implantation according to lens status. Methods This was a retrospective single-centre study involving 132 eyes of 66 participants who had undergone intraocular pressure (IOP)-lowering XEN45 Gel Stent implantation, either as a standalone procedure in phakic and pseudophakic eyes or in combination with phacoemulsification. Successful surgery was defined by three scores: IOP at follow-up < 21 mmHg (score A) or < 18 mmHg (score B) and an IOP reduction > 20% or IOP ≤ 15 mmHg and an IOP reduction ≥ 40% (score C). In all scores, one open conjunctival revision was allowed, and additional repeat surgery was considered a failure. The predictability of success and revision rate depending on the outcome of the first eye were calculated using Bayes’ theorem. Results IOP-lowering did not differ significantly between the first and second eyes. Success rates of standalone surgery in the second eye after successful surgery in the first eye significantly exceed rates after prior failure. For the combined procedure, the rates did not differ significantly. For score A, we determined a 76.6% chance of success following a prior success and a 57.9% chance, if prior surgery failed. The corresponding probabilities were 75% and 59.1% for score B, while 66.7% and 15.7% for score C, respectively. We calculated a 60% risk for revision surgery in the standalone phakic group. If the first eye was not revised, the risk of revision in the subsequent eye was 20%. The corresponding risks were 72.7% and 5% for the standalone procedure in pseudophakic patients and 38.4% and 41.7% for the combined procedure, respectively. Conclusion The results of our study offer a tool to predict the outcome of subsequent eye surgeries based on either the outcome in the initial eye and the type of surgery performed, owing to the high predictive potential.

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Intra-individual comparison after combined phaco-trabecular aspiration in pairs of pseudoexfoliative eyes

Abstract: The postoperative outcome in an eye after combined phaco-trabecular aspiration is predictive for the second eye. If this procedure succeeded in the first eye, the prognosis for the same strategy in the fellow eye is also good.

Cited by 10 publications

References 17 publications

Predictability of ab‐interno trabeculectomy success in the subsequent eye: A contralateral eye comparison study

Predictability of ab‐interno trabeculectomy success in the subsequent eye: A contralateral eye comparison study

Trabeculectomy Using Mitomycin C versus an Atelocollagen Implant: Clinical Results of a Randomized Trial and Histopathologic Findings

Predictability of success and open conjunctival revision rates in the subsequent eye after XEN45 Gel Stent implantation according to lens status

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