Intra-parotid facial nerve multiple plexiform neurofibroma in patient with NF1

Fadda, Maria Teresa; Verdino, G.; Mustazza, Maria Cristina; Bartoli, Davina; Iannetti, Giorgio

doi:10.1016/j.ijporl.2008.01.022

Cited by 21 publications

(26 citation statements)

References 34 publications

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“…Although no documented case has been made of a plexiform neurofibroma on the soft palate, it has been described in the oral cavity including the lower lip [19], tongue and oropharynx [9]. Plexiform neurofibroma has also been found in the maxillary sinus [8], intraparotid [7], and arytenoid [10]. These cases presented with a mass gradually progressing in size, not associated with pain similar to our case [9,19].…”

Section: Discussionsupporting

confidence: 67%

“…One study states that plexiform neurofibromas are typically congenital, with approximately 50% occurring in the region of the head, neck, face, larynx [7]. Although no documented case has been made of a plexiform neurofibroma on the soft palate, it has been described in the oral cavity including the lower lip [19], tongue and oropharynx [9].…”

Section: Discussionmentioning

confidence: 99%

“…Morphological features of a plexiform neurofibroma with an immunoreactivity profile for desmin and smooth muscle actin produces a rare variant of a benign plexiform lesion called plexiform leiomyoma. Plexiform leiomyoma's presence has only been documented in the uterus and esophagus [1][2][3][4][5][6][7][8][9][10][11]. The following case study demonstrates the first ever finding of a plexiform leiomyoma outside the gastrointestinal tract and uterus located on the soft palate.…”

Section: Introductionmentioning

confidence: 99%

“…Plexiform neurofibroma is another plexiform tumor shown to have predilection for the head and neck region. Case reports have shown plexiform neurofibromas in areas including, but not limited to the neck, parotid gland, aretynoid, maxillary sinus, and tongue [6][7][8][9][10]. Morphological features of a plexiform neurofibroma with an immunoreactivity profile for desmin and smooth muscle actin produces a rare variant of a benign plexiform lesion called plexiform leiomyoma.…”

Section: Introductionmentioning

confidence: 99%

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Plexiform Leiomyoma of the Soft Palate: A Case Study and Literature Review

Kartike¹

2016

JOENTR

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Purpose: To present a case of Plexiform Leiomyoma found in the soft palate, the first ever documented subsite, as well as formulate management protocols by inferring relationships to similar lesions. Method:Case study and review of English literature on plexiform leiomyoma along with various benign plexiform lesions. Result:We report a case of plexiform leiomyoma, which was found in the soft palate after the patient presented incidentally with concurrent hypertrophic tonsillitis having signs of odynophagia, sleep disordered breathing, and chronic sore throat. After bilateral tonsillectomy and complete excisional biopsy of soft palate mass, the entity was found, and through literature review of similar tumors, managed correctly. Conclusion:The head and neck region is a rare subsite for a benign plexiform lesion. The most common plexiform lesion is the plexiform neurofibroma in the head and neck. The case discusses the different benign plexiform lesions in the head and neck region, and plexiform leiomyoma found in all regions of the body, to help draw possible insight on management as well as review the differences between these lesions. Keywords:

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Section: Discussionsupporting

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Plexiform Leiomyoma of the Soft Palate: A Case Study and Literature Review

Kartike¹

2016

JOENTR

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“…If plexiform neuroma is found, it is more interesting that more than one segment of the facial nerve may be affected. Fadda et al [6] reported that there were only 11 cases with intraparotid facial nerve neurofibromas in the English literature. To the best of our knowledge, one of the three cases in our study is the first case report with a neurofibroma of the facial nerve involving both intratemporal and intraparotid segments in the literature.…”

Section: Introductionmentioning

confidence: 99%

Neurofibroma around the Ear Canal: Report of Three Cases

Satar¹,

Hıdır²,

Aşık³

et al. 2016

Int Adv Otol

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Facial nerve neurofibromas are an uncommon entity, particularly in the intraparotid region. Three cases are presented herein, including the first reported case of both an intratemporal and intraparotid facial nerve malignant neurofibroma. To the best of our knowledge, this is the first medical publication to describe a neurofibroma involving both the intratemporal and intraparotid regions. The aim of this clinical record was to present the surgical experiences in three cases of intratemporal and intraparotid facial neurofibroma. Of the three cases of neurofibroma included in this report, the first case was a 30-year-old male who initially presented with a parotid mass without facial dysfunction. The other two cases were intratemporal neurofibromas, one of which was confirmed as a plexiform neurofibroma by pathology. These tumors often involve two or more segments of the facial nerve. The outcomes of these tumors are closely related to nerve integrity, preoperative facial nerve function level, and the follow-up period. Neurofibromas are most commonly found with neurofibromatosis type 1 and are characterized by incorporation of the nerve fibers within their matrix. Presentation of the intratemporal facial neurofibromas is variable, with facial palsy most common. Furthermore, the incidence of a solitary neurofibroma of the facial nerve originating in the parotid region is extremely low.

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Plexiform Neurofibroma of Head and Neck

2017

Diagnostic Imaging: Head and Neck

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Intra-parotid facial nerve multiple plexiform neurofibroma in patient with NF1

Cited by 21 publications

References 34 publications

Plexiform Leiomyoma of the Soft Palate: A Case Study and Literature Review

Plexiform Leiomyoma of the Soft Palate: A Case Study and Literature Review

Neurofibroma around the Ear Canal: Report of Three Cases

Plexiform Neurofibroma of Head and Neck

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