Intradural Extramedullary Ewing's Sarcoma Recurrence with Acute Clinical Presentation and Literature Review

Abstract

SUMMARY -The intradural extramedullary space is an extremely unusual site for the onset of Ewing's sarcoma. We describe a case of recurrence of intradural extramedullary Ewing's sarcoma and review the literature available on this topic.

Clinicopathological representation of nonmetastatic Ewing sarcoma of the scapula - a case study

“…7 A gradual increase of pain is one of the major symptoms of bone sarcomas. 8 In the present case, the patient doesn't have a complaint of pain. This may be due to the early stage of the disease condition.…”

Primary Spinal Intradural Extraosseous Ewing Sarcoma in a Pediatric Patient: Case Report and Review of the Literature

“…The tumor was in the paravertebral tissues and had a histologic similarity to ES. While paravertebral, extremity, and pelvic locations have been commonly reported, intradural spinal ES is extremely rare [1, 3, 4, 8-10]. ES in this location may be histologically confused with the central PNET family, such as pineoblastoma, supratentorial PNET, and medulloblastoma.…”

“…A primary spinal, intradural, extramedullary EES is extremely uncommon in the pediatric population [1, 3, 4, 8-10]. The authors report the rare case of a 14-year-old female presenting with a hemorrhagic ES involving the conus medullaris.…”

“…The overall incidence of ES in the US population is estimated to be 2.93 per 1 million. ES has a predominance in the Caucasian population and occurs more often in males, especially as age increases [3]. However, extraosseous ES (EES) is reported to occur equally in both sexes [4].…”

“…An estimated 25% of patients with ES will have detectable metastasis at the time of diagnosis. Spinal column metastasis occurs in 3.5–7% of cases [3]. EES represents 16% of all cases; tumors have been reported in the paravertebral soft tissues, lower extremities, chest wall, and pelvis [1-7].…”