Intralesional steroid injection: an alternative treatment option for vocal process granuloma in ten patients

Comprehensive Outcome Researches of Intralesional Steroid Injection on Benign Vocal Fold Lesions

“…Under visual guidance, 0.1 mL, 1:1 mixture of triamcinolone acetonide (10 mg/mL) and dexamethasone sodium phosphate (5 mg/mL) was injected by curved injection needle (Model 16-50050, Medtronic Xomed Jacksonville, Florida, USA) into the Reinke's space of the vocal lesions. 22 For patients who were intolerant of the above transoral procedure, 23 transnasal injection via the working channel of a flexible nasopharyngoscope could be applied with an endoscopic injection apparatus (Model NM-101C-0427 Olympus, Aomori, Japan. ), which includes a reusable metallic external sheath (MAJ-655) and a disposable flexible needle tract with a 27G rigid tip (MAJ-656).…”

Comparison of benign lesion regression following vocal fold steroid injection and vocal hygiene education

“…Intralesional steroid injection has been advocated in the management of inflammatory laryngeal diseases, such as sarcoidosis, systemic lupus erythematosus, and Wegener's granulomatosis . In recent decades, various studies have documented the potential role of VFSI in treating benign vocal pathologies, including nodules, polyps, scar, and vocal process granuloma . Although various measuring parameters, for example, maximal phonation time and voice handicap index, has been applied to evaluate outcomes in previous studies of VFSI, the actual lesion regression in size following VFSI has rarely been reported.…”

In‐office procedures for the treatment of benign vocal fold lesions in the awake patient: A contemporary review

“…Because vocal process granuloma involves chronic inflammation, ISI may be particularly well suited for this lesion . Monthly ISI for refractory granuloma achieved resolution of the lesion in 60% after 6 months of treatment, with significant size reduction in the remainder . Although promising, these reports are limited.…”