Intraocular cholesterol crystals

Khan, Imran; Parulekar, Manoj

doi:10.1136/postgradmedj-2013-132129

Cited by 4 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anterior chamber cholesterolosis, with polychromatic shining crystals presenting in anterior chamber, is an interesting and uncommon condition which can occur in eyes suffering from vitreous hemorrhage, hyphema, long-standing retinal detachment, chronic intraocular inflammation, and Coats disease [1][2][3][4][5]. Anterior chamber cholesterolosis secondary to Eales' disease is extremely rare [6].…”

Section: Introductionmentioning

confidence: 99%

Ultrasound findings in a case of Eales’ disease and ocular trauma with anterior chamber cholesterolosis

Lü

Huang

2020

BMC Ophthalmol

View full text Add to dashboard Cite

Background Anterior chamber cholesterolosis is a rare phenomenon which occurs mostly in chronically blind eyes. We present the anterior and posterior ultrasound findings in a case of anterior chamber cholesterolosis secondary to Eales’ disease and ocular trauma, which may contribute to the understanding of the potential mechanism of this phenomenon. Case presentation A 48-year-old man presented with “sparking” right eye, which appeared soon after the ocular trauma. Both eyes were confirmed Eales’ disease in our center 8 years ago, and right eye remained no light perception since then. Intraocular pressure of right eye measured by Goldmann applanation tonometry was 1 mmHg. Slitlamp photograph revealed multiple polychromatic large crystals in anterior chamber. Ultrasound biomicroscopy showed that anterior chamber was filled with extensive large granular substances. Dense dotted hyperechoic foci and retinal detachment was found in B-scan ultrasound examination. The right eye was diagnosed as anterior chamber cholesterolosis secondary to Eales’ disease and ocular trauma. The patient was asymptomatic, and therefore was advised to have regular follow-up. Conclusion The findings of above imaging examinations, as well as complaint of “sparkling” eye appeared soon after ocular trauma elucidate that anterior chamber cholesterol crystals were from vitreous cavity. Any factors facilitating the communication of anterior chamber and vitreous body may lead to the occurrence of this rare phenomenon in predisposing eyes. The anterior and posterior ultrasound findings may give a clue on the potential mechanism.

show abstract

Section: Introductionmentioning

confidence: 99%

Ultrasound findings in a case of Eales’ disease and ocular trauma with anterior chamber cholesterolosis

Lü

Huang

2020

BMC Ophthalmol

View full text Add to dashboard Cite

show abstract

In vitro determination of the solubility limit of cholesterol in phospholipid bilayers

2016

Chemistry and Physics of Lipids

View full text Add to dashboard Cite

Cholesterol has limited solubility in phospholipid bilayers. The solubility limit is strongly dependent on the nature of the lipid with which the cholesterol is mixed while properties of the crystals formed can be modified by phospholipid-cholesterol interactions. In this review we summarize the various methods that have been developed to prepare hydrated mixtures of cholesterol and phospholipid. We point out some of the factors that determine the form adopted when cholesterol crystallizes in such mixtures, i.e. two- or three-dimensional, monohydrate or anhydrous. These differences can greatly affect the ability to experimentally detect the presence of these crystals in a membrane. Several methods for detecting cholesterol crystals are discussed and compared including DSC, X-ray and GIXRD diffraction methods, NMR and EPR spectroscopy. The importance of the history of the sample in determining the amount and nature of the cholesterol crystals formed is emphasized.

show abstract

In vitro determination of the solubility limit of cholesterol in phospholipid bilayers

Epand

Bach

Wachtel

2016

Chemistry and Physics of Lipids

View full text Add to dashboard Cite

Intraocular cholesterol crystals

Cited by 4 publications

References 9 publications

Ultrasound findings in a case of Eales’ disease and ocular trauma with anterior chamber cholesterolosis

Ultrasound findings in a case of Eales’ disease and ocular trauma with anterior chamber cholesterolosis

In vitro determination of the solubility limit of cholesterol in phospholipid bilayers

In vitro determination of the solubility limit of cholesterol in phospholipid bilayers

Contact Info

Product

Resources

About