Intraoperative Mitomycin C Use During Filtration Surgery and Lacrimal Drainage System Obstruction

Kashkouli, Mohsen Bahmani; Parvaresh, Mohammah Mehdi; Mirzajani, Hoora; Astaraki, Arezoo; Falavarjani, Khalil Ghasemi; Ahadian, Ali

doi:10.1016/j.ajo.2008.08.037

Cited by 7 publications

(7 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Öte yandan, mitomisin-C'nin glokom cerrahisinde skleral yatağa uygulanmasının PS'nda ek bir artış yaratmadığı gösterilmiştir [24]. PS'nun, 5-florourasil ve dosetaksel gibi sistemik kemoterapötik ajanların kullanımında da geliştiği bildirilmiştir [25,26].…”

Section: Etyolojiunclassified

Akkiz punktum stenozunda tanı, etyoloji ve tedavi seçenekleri

Ilhan¹

2020

Pamukkale Medical Journal

View full text Add to dashboard Cite

Makale bilim dalı: Göz Hastalıkları Başlık: Akkiz punktum stenozunda tanı, etyoloji ve tedavi seçenekleri. Kısa başlık: Akkiz punktum stenozu. Özet: Punktum stenozu, önemli bir epifora nedenidir. Konjenital olabilse de daha çok akkiz görülen, kanalikülün eksternal açıklığının daralmasıdır. Punktum açıklığı, tam tıkanıklığa kadar farklı genişliklerde ve şekillerde görülebilir. İdiyopatik ve involüsyonel başta olmak üzere kronik enflamatuar sürece yol açan lokal ve sistemik enflamatuar hastalıklar, kapak malformasyonları, topikal ve sistemik ilaç kullanımı ve enfeksiyonlara bağlı olarak punktum stenozu gelişmektedir. Punktum stenozunun tedavisinde, kanalikülün proksimali ve eksternal açıklığın genişletilmesine yönelik Snip ampulloplasti, Panç ampulloplasti ve genişliğin devamının sağlanması amacıyla delikli punktum tıkaçları, stent kullanımları gibi etkili olduğu gösterilen minimal cerrahi yöntemler uygulanmaktadır. Hastaların önemli bölümü başarılı bir şekilde tedavi edilse de, bazı hastalarda punktum stenozunun tekrarladığı görülmektedir. Akkiz punktum stenozunun nedenlerinin, klinik yaklaşım ve tedavi seçeneklerinin bilinmesi bu patoloji nedenli epiforanın tedavisinde başarı için gereklidir.

show abstract

Section: Etyolojiunclassified

Akkiz punktum stenozunda tanı, etyoloji ve tedavi seçenekleri

Ilhan¹

2020

Pamukkale Medical Journal

View full text Add to dashboard Cite

show abstract

“…There are some reports of upper lacrimal drainage system obstruction associated with topical MMC, used in glaucoma filtering surgery and ocular surface neoplasia 12. However, Kashkouli et al .,67 conducted a comparative study and concluded that there was no significant effect of topical MMC, used during filtration surgery, on lacrimal system obstruction. Canalicular obstruction could also occur after photodynamic therapy with verteporfin, used for treating choroidal neovascular membranes 68…”

Section: Canalicular Stenosismentioning

confidence: 99%

Assessment and management of proximal and incomplete symptomatic obstruction of the lacrimal drainage system

Kashkouli

Pakdel

Kiavash

2012

Middle East Afr J Ophthalmol

View full text Add to dashboard Cite

Epiphora is a common complaint of patients who present to an Ophthalmology Clinic. In many cases, epiphora is due to an obstruction in the lacrimal drainage system. However, a subgroup of symptomatic patients with epiphora has a patent lacrimal drainage system. Such cases are usually termed ‘functional obstruction’ and / or ‘stenosis of the lacrimal drainage system’. Various etiologies and diagnostic and therapeutic approaches have been described in literature, which implies the lack of a standardized approach. This article will review the evolving diagnostic and therapeutic approaches in literature, and in the end, propose a paradigm in approaching this group of patients.

show abstract

“…Nevertheless, the half-life of MMC is very short, only a few hours, limit its application [10][11], and make repeating administration necessary in clinic but which resulted in heavy side effect. In order to maintain an effective drug concentration for an appropriate period of time, sponge and amnia MMC delivery pieces were often used to implant subconjunctival lamella or sub-sclera lamella [12][13].…”

Section: Introductionmentioning

confidence: 99%

Drug efficiency of a novel anti-proliferative conjugate: Periodate-oxidized chitosan-g-mitomycin C

Duan

Zheng

et al. 2011

2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)

View full text Add to dashboard Cite

Mitomycin C is an anti-proliferative agent which is usually adopted to prevent fibroblast proliferation in trabeculectomy. However, the shorter half-life of Mitomycin C limits its use. In this paper, a novel anti-proliferative conjugate was synthesized by Schiff base reaction. The cytotoxicity of periodate-oxidized chitosan and drug efficiency were also performed by cell proliferation assay, flow cytometry. The results clearly suggested that the conjugate: periodate-oxidized chitosang-mitomycin C could be a suitable polymeric system for controlling the release of mitomycin C.

show abstract

Intraoperative Mitomycin C Use During Filtration Surgery and Lacrimal Drainage System Obstruction

Cited by 7 publications

References 14 publications

Akkiz punktum stenozunda tanı, etyoloji ve tedavi seçenekleri

Akkiz punktum stenozunda tanı, etyoloji ve tedavi seçenekleri

Assessment and management of proximal and incomplete symptomatic obstruction of the lacrimal drainage system

Drug efficiency of a novel anti-proliferative conjugate: Periodate-oxidized chitosan-g-mitomycin C

Contact Info

Product

Resources

About