2012
DOI: 10.1007/s10143-012-0376-3
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Intraoperative template-molded bone flap reconstruction for patient-specific cranioplasty

Abstract: Cranioplasty is a common neurosurgical procedure. Free-hand molding of polymethyl methacrylate (PMMA) cement into complex three-dimensional shapes is often time-consuming and may result in disappointing cosmetic outcomes. Computer-assisted patient-specific implants address these disadvantages but are associated with long production times and high costs. In this study, we evaluated the clinical, radiological, and cosmetic outcomes of a timesaving and inexpensive intraoperative method to mold custom-made implant… Show more

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Cited by 58 publications
(37 citation statements)
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“…Key advantages of use lie in high immunological compatibility [36], as the implant is comprised of the patient's own tissue, as well as superior anatomical cosmesis, given it matches the injury profile directly [29]. Often, direct re-implantation of the autologous bone flap is not feasible and storage (either cryogenic or subcutaneous) is required to ensure the flap is preserved until re-implantation [21,68,69].…”
Section: Discussionmentioning
confidence: 99%
“…Key advantages of use lie in high immunological compatibility [36], as the implant is comprised of the patient's own tissue, as well as superior anatomical cosmesis, given it matches the injury profile directly [29]. Often, direct re-implantation of the autologous bone flap is not feasible and storage (either cryogenic or subcutaneous) is required to ensure the flap is preserved until re-implantation [21,68,69].…”
Section: Discussionmentioning
confidence: 99%
“…4 While the polymer sets, it can be moulded into a specific shape. 5 Once hardened and cooled, it is safe for implant into humans. 5,6 The exothermic curing process of the PMMA poses a challenge for use in cranioplasty as the paste cannot be held against the cranial defect to mould due to risk of thermal injury to the brain.…”
Section: Introductionmentioning
confidence: 99%
“…5 Once hardened and cooled, it is safe for implant into humans. 5,6 The exothermic curing process of the PMMA poses a challenge for use in cranioplasty as the paste cannot be held against the cranial defect to mould due to risk of thermal injury to the brain. 2 The extreme temperatures also create difficulty in handling the paste, often leading to unsatisfactory cosmetic results.…”
Section: Introductionmentioning
confidence: 99%
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“…There are several techniques and materials available for preservation of the explanted bone-flap and its replacement [2,5,7,12,13,[16][17][18]. These techniques differ in functionality, cosmetic result, costs and spectrum of complications involved in the procedures.…”
Section: Introductionmentioning
confidence: 99%