Intrasubject Physiologic Variability in 24 Hour Esophageal Acid Exposure

Transcriptional regulation of ABC drug transporters

“…FXR, when combined with RXR and bile salts as its ligand, initiates feedback control of bile acid synthesis (Redinger, 2003). Both BSEP and MRP2 are targets of the FXR : RXR heterodimer.…”