Intratympanic Steroids for Sudden Sensorineural Hearing Loss

Spear, Samuel A.; Schwartz, Seth

doi:10.1177/0194599811419466

Cited by 116 publications

(85 citation statements)

References 46 publications

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“…4 The mean improvement in pure tone average in the IT steroid group ranged from 15-30dB compared to 0-15dB in controls. The mean benefit of IT steroid relative to controls was 13dB.…”

Section: Treatmentmentioning

confidence: 91%

“…There are a large number of papers investigating the influence of IT steroids for the management of SSNHL. 4 However, many of the studies are flawed, not least because up to 60% of SSNHL can make some degree of spontaneous recovery and large scale studies are required to obtain useful results in what is a fairly rare condition.…”

Section: Treatmentmentioning

confidence: 99%

“…Some evidence suggests that IT steroid therapy is more useful to salvage hearing following ineffective oral steroid therapy than if it had been used as a primary treatment. 4,5 Various types of steroids have been used but there is no evidence that one is better than another. The key is to treat early.…”

Section: Treatmentmentioning

confidence: 99%

See 2 more Smart Citations

Sudden sensorineural hearing loss: early diagnosis improves outcome

Lloyd

2013

Br J Gen Pract

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“…4 The mean improvement in pure tone average in the IT steroid group ranged from 15-30dB compared to 0-15dB in controls. The mean benefit of IT steroid relative to controls was 13dB.…”

Section: Treatmentmentioning

confidence: 91%

Section: Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Sudden sensorineural hearing loss: early diagnosis improves outcome

Lloyd

2013

Br J Gen Pract

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“…[16,18,19]. In sudden sensorineural hearing loss, where a neuritis is rarely assumed to be the cause, intratympanic corticosteroid application is widely accepted for salvage treatment with sufficient evidence in several studies including meta-analyses [38].…”

Section: Discussionmentioning

confidence: 99%

About the pathophysiology of acute unilateral vestibular deficit – vestibular neuritis (VN) or peripheral vestibulopathy (PVP)?

Uffer

Hegemann

2016

VES

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“…The efficacy of this treatment, which is called intratympanic steroid treatment (ITS) in the literature, has been reported in many studies (13,14). However, the timing of this therapy is controversial.…”

Section: Introductionmentioning

confidence: 99%

Can Intratympanic Steroid Be Initial Therapy for Sudden Sensorineural Hearing Loss?

Ocak¹,

Beton²,

Kesici³

et al. 2014

Turk Arch Otolaryngol

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Objective: To evaluate the efficacy of intratympanic steroid treatment with concurrent systemic steroids as an initial therapy for sudden sensorineural hearing loss (SSNHL). Methods:Patients who were diagnosed as idiopathic SSNHL and received no therapy were included in the study. Patients were divided into control and study groups. Patients in the study group received concurrent intratympanic steroid treatment with systemic steroid therapy. Patients in the control group received standard systemic steroid treatment alone. The duration of time before the treatment was evaluated for all the patients. Pure tone audiometry (PTA) was performed for all the patients in the pre-treatment and post-treatment period in order to record the responses for both in terms of the individual frequencies and the pure tone average. Results:Twenty nine patients (16 female and 13 male) with a mean age of 43.6 years were enrolled in the study.There was 15 patients in the study group and 14 patients in the control group. The mean duration of time for the initial therapy was 4 days for the control group and 6.5 days for the study group (p=0.125). The mean recovery in PTA for the control group was 10.29±4.10 decibel (dB) (0-15) while it was 19.40±18.84 dB (3-68) for the study group (p=0.003). Conclusion:At the end of treatment, significantly better hearing results were obtained for the patients in the study group when compared to the control group both for PTA and all the frequencies individually. We suggest that concurrent intratympanic steroids with systemic steroid therapy gives better hearing results than the standard systemic therapy alone.

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Intratympanic Steroids for Sudden Sensorineural Hearing Loss

Cited by 116 publications

References 46 publications

Sudden sensorineural hearing loss: early diagnosis improves outcome

Sudden sensorineural hearing loss: early diagnosis improves outcome

About the pathophysiology of acute unilateral vestibular deficit – vestibular neuritis (VN) or peripheral vestibulopathy (PVP)?

Can Intratympanic Steroid Be Initial Therapy for Sudden Sensorineural Hearing Loss?

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