Intravascular Optical Coherence Tomography: Comparison with Histopathology in Atherosclerotic Peripheral Artery Specimens

Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography

“…Development of scanning catheters has enabled endoscopic OCT imaging of internal organs and extended the OCT study field further [9,10]. Endoscopic OCT imaging has demonstrated its ability to resolve layered tissue structures, and to differentiate normal from certain pathologic conditions within the esophagus [11][12][13][14][15][16], coronary artery [17][18][19] and other internal organs such as the oral cavity [20], larynx [21][22][23], and bladder [24].…”

Catheter-based intraluminal optical coherence tomography: comparison with digital light microscopy of ureter wall morphometry in porcine specimens

“…Biological tissues other than the vitreous body of the eye, such as human skin or vessel walls, strongly scatter NIR light but allow for OCT measurements with a sub-surface depth of up to 2 mm [1,3,4]. Catheter-based OCT devices have been developed to study blood vessels and hollow organs from inside their lumen in real time, with a spatial resolution of less than 20 µm [2][3][4][5][6]. In urology, OCT applications focus on the urinary bladder.…”

Carotid atherosclerotic plaque characterisation by measurement of ultrasound sound speed in vitro at high frequency, 20MHz

“…Optical coherence tomography (OCT) is being researched (Meissner et al 2006;Yabushita et al 2002) in the diagnosis of peripheral arterial diseases but improvements are needed in signal-to-noise ratio (Farooq 2009). As OCT is capable of both high resolution and contrast, the macrophage content can be quantified (Tearney et al 2003) and therefore may be a good risk indicator.…”