2015
DOI: 10.5624/isd.2015.45.1.31
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Intravenous contrast media application using cone-beam computed tomography in a rabbit model

Abstract: PurposeThis study was performed to evaluate the feasibility of visualizing soft tissue lesions and vascular structures using contrast-enhanced cone-beam computed tomography (CE-CBCT) after the intravenous administration of a contrast medium in an animal model.Materials and MethodsCBCT was performed on six rabbits after a contrast medium was administered using an injection dose of 2 mL/kg body weight and an injection rate of 1 mL/s via the ear vein or femoral vein under general anesthesia. Artificial soft tissu… Show more

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Cited by 11 publications
(8 citation statements)
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“…29 Despite the poorer soft tissue contrast of CBCT, compared with that of conventional CT, evaluation of the soft tissue is still possible. A study 30 to evaluate maxillofacial soft tissue by IV administration of iodinated contrast media and CBCT was conducted with rabbits. Authors of that study 30 concluded that small, strongly contrastenhancing lesions and anatomic structures, such as blood vessels, can be detected.…”
Section: Discussionmentioning
confidence: 99%
“…29 Despite the poorer soft tissue contrast of CBCT, compared with that of conventional CT, evaluation of the soft tissue is still possible. A study 30 to evaluate maxillofacial soft tissue by IV administration of iodinated contrast media and CBCT was conducted with rabbits. Authors of that study 30 concluded that small, strongly contrastenhancing lesions and anatomic structures, such as blood vessels, can be detected.…”
Section: Discussionmentioning
confidence: 99%
“…29 Despite the poorer soft tissue contrast of CBCT, compared with that of conventional CT, evaluation of the soft tissue is still possible. A study 30 to evaluate maxillofacial soft tissue by IV administration of iodinated contrast media and CBCT was conducted with rabbits. Authors of that study 30 concluded that small, strongly contrastenhancing lesions and anatomic structures, such as blood vessels, can be detected.…”
Section: Discussionmentioning
confidence: 99%
“…A study 30 to evaluate maxillofacial soft tissue by IV administration of iodinated contrast media and CBCT was conducted with rabbits. Authors of that study 30 concluded that small, strongly contrastenhancing lesions and anatomic structures, such as blood vessels, can be detected. However, the use of contrast administration in dogs and cats for evaluation of maxillofacial soft tissue-associated diseases (eg, tumors, abscesses, or cysts) by use of CBCT has not yet been described.…”
Section: Discussionmentioning
confidence: 99%
“…CBCT scan is optimized to image the osseous maxillofacial features rather than the soft tissue, but evaluation of the soft tissue is still possible. Despite the poorer contrast resolution of CBCT compared to conventional CT, contrast enhancement of small blood vessels in an experimentally induced lesion can be detected following intravenous iodinated contrast administration in rabbits ( 23 ). The utility of contrast administration for CBCT of clinical rabbit patients with naturally occurring disease has not yet been described.…”
Section: Discussionmentioning
confidence: 99%