“…Typically, the holographic sensors are deposited on a substrate that restricts their swelling or shrinkage, in a lateral direction, due to the presence of the analyte. Furthermore, because they are coated on a substrate, all sensors reported in the literature are practically flat layers [ 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ]. For example, in [ 36 ], a holographic sensor with changing optical properties as the result of a biochemical reaction between the hologram/hologram support medium and the analyte species was introduced.…”