Industry 4.0 is an intelligent manufacturing system, which focuses on the design, manufacturing and in providing customized product & services as per the individual requirements. It encourages the integration of different intelligent manufacturing systems and advanced information technologies and is also known as the fourth revolution. Customization of products is an important issue in orthopaedics and is well taken by the Industry 4.0, as it can make manufacturing systems intelligent & responsive to customer's need and the delight. 1 We are contemplating extensive research in this crucial area through different components of Industry 4.0. Industry 4.0 is anticipated to be operational from 2020 and may realize its extensive capability to fulfill the future needs of the medical and their associated fields. It is highly dependent on innovations like additive manufacturing technologies, process automation, Internet of Things (IoT), artificial intelligence, big data, automation, virtual reality, and robotics. 2 It is a new phase of development to create new developments in the various medical fields, including orthopaedics. It is supposed to impact the environment extensively by reducing wastage of material and human efforts with the help of various advanced innovative technologies. Product customization is the desired requirement in orthopaedics because patient-specific implants and devices vary from