Intussusception as Rare Presenting Sign of Pediatric Celiac Disease

Shoshany, Cory; Fahey, Lisa M.

doi:10.1097/mpg.0000000000003699

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…Among these, we highlight intestinal intussusception. Although its clear frequency could not yet be established, the association between the two pathologies is certified by numerous reported cases (151)(152)(153)(154). It is noted that the risk factors associated with this are age and low weight, diarrhea at presentation, abdominal distension, rickets, low serum albumin, severe villous atrophy and refeeding syndrome (155,156).…”

Section: Systemic Damagementioning

confidence: 99%

Celiac disease - a pluripathological model in pediatric practice

Lupu,

Sasaran,

Jechel

et al. 2024

Front. Immunol.

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Being defined as an autoimmune, chronic pathology, frequently encountered in any age group, but especially in pediatrics, celiac disease (also called gluten enteropathy), is gaining more and more ground in terms of diagnosis, but also interest in research. The data from the literature of the last decades attest the chameleonic way of its presentation, there may be both classic onset symptoms and atypical symptoms. Given the impact played by celiac disease, especially in the optimal growth and development of children, the current narrative review aims to highlight the atypical presentation methods, intended to guide the clinician towards the inclusion of the pathology in the differential diagnosis scheme. To these we add the summary presentation of the general data and therapeutic lines regarding the underlying condition and the existing comorbidities. In order to place the related information up to date, we performed a literature review of the recent articles published in international databases. We bring forward the current theories and approaches regarding both classic celiac disease and its atypical manifestations. Among these we note mainly constitutional, skin or mucous, bone, neuro-psychic, renal, reproductive injuries, but also disorders of biological constants and association with multiple autoimmunities. Knowing and correlating them with celiac disease is the key to optimal management of patients, thus reducing the subsequent burden of the disease.

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Section: Systemic Damagementioning

confidence: 99%

Celiac disease - a pluripathological model in pediatric practice

Lupu,

Sasaran,

Jechel

et al. 2024

Front. Immunol.

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“…[1][2][3] The most common type is ileocecal junction intussusception. 4,5 Most cases are primary intussusception, which can easily recur and result in intestinal obstruction or necrosis. 6 In clinical practice, the main treatment methods are pneumatic reduction under X-ray fluoroscopy and water enema under ultrasound guidance.…”

Section: Introductionmentioning

confidence: 99%

Developing a Nomogram for Predicting Surgical Intervention in Pediatric Intussusception After Pneumatic Reduction: A Multicenter Study from China

Liu,

Wang,

Jiang

et al. 2024

TCRM

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Purpose The objective of this study was to develop and validate a nomogram for predicting the need for surgical intervention in pediatric intussusception after pneumatic reduction. Patients and Methods This retrospective study analyzed the clinical data of children with acute intussusception admitted to four hospitals in China from January 2019 to January 2022. Based on the results of pneumatic reduction, the patients were divided into two groups: the successful reduction group (control group) and the failed reduction group (operation group). The total sample was randomly divided into a training set and a validation set in a 7:3 ratio. Logistic regression analysis was performed to establish a predictive model for surgical risk. Results A total of 1041 samples were included in this study, with 852 in the control group and 189 in the operation group. Among the total sample, 728 cases were used for training and 313 cases were used for validation. Logistic regression analysis of the training set identified age, time of abdominal pain, presence or absence of hematostoecia, C-reactive protein value from blood test on admission, and nested position indicated by B-ultrasound as independent predictors of intussusception intervention. Based on the five independent risk factors identified through multivariate logistic regression, a nomogram was successfully constructed to predict the failure of resetting by air enema under X-ray. Conclusion A nomogram was developed to predict the need for surgical intervention after intussusception pneumatic reduction in children. The nomogram was based on clinical risk factors including age, time of abdominal pain, presence or absence of blood in stool, value of C-reactive protein in blood test on admission, and nested position indicated by B-ultrasound. Our internal validation demonstrated that this nomogram can serve as a useful tool for identifying risk factors associated with failure of air enema in children with intussusception.

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Intussusception as Rare Presenting Sign of Pediatric Celiac Disease

Cited by 2 publications

References 6 publications

Celiac disease - a pluripathological model in pediatric practice

Celiac disease - a pluripathological model in pediatric practice

Developing a Nomogram for Predicting Surgical Intervention in Pediatric Intussusception After Pneumatic Reduction: A Multicenter Study from China

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