Invasive methods and clinical follow-up to esimate HP eradication success

Michopoulos, Spyros; Balta, Ahmet Ziya; Mentis, Αndreas; Sotiropoulou, Maria; Miriagou, Vivì; Papaspyrou, Irene; Bouzakis, H.; Tsibouris, Panayiotis; Kralios, N.

doi:10.1016/s0016-5085(98)80923-2

Cited by 2 publications

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“…Post‐therapeutically, the rapid urease test is thought to present 86% sensitivity when histology is thought to be the gold standard 26 . Nevertheless, when we have taken into consideration long‐term follow‐up and various diagnostic tests in our unit, histology did not seem to represent the gold standard to validate conflicting results between the rapid urease test and histology 27 . Thus for this group of patients, the 13 C‐urea breath test was chosen as an additional test; this is considered as reliable as histology in everyday practice and seemed to be ideal for overcoming low histology sensitivity in our laboratory 28…”

Section: Discussionmentioning

confidence: 97%

Randomized study comparing omeprazole with ranitidine as anti‐secretory agents combined in quadruple second‐line Helicobacter pylori eradication regimens

Michopoulos

Tsibouris

Bouzakis

et al. 2000

Aliment Pharmacol Ther

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The pathogenic role of Helicobacter pylori in chronic active gastritis and its association with duodenal ulcer disease in 95±99% of patients is well established. 1 Therefore the 1994 National Institute of Health (NIH) consensus development conference recommended the eradication of H. pylori in all patients with documented peptic ulcer disease. 2 The ideal eradication regimen remains elusive; previously used double regimens (omeprazole plus amoxycillin) had a success rate ranging from 30 to 80%. 3 The aim of this study was to compare the ef®cacy of either omeprazole or ranitidine combined in a quadruple regimen including tripotassium dicitrato bismuth, metronidazole and tetracycline hydrocloride as a second-line treatment in patients with erosive duodenitis or duodenal ulcer in whom a non-metronidazole-based anti-H. pylori therapy had previously failed. Currently used eradication regimens show ef®cacy ranging from 80 to 95%. 4 Quadruple therapy comprising a proton pump inhibitor in combination with bismuth triple therapy appears to produce the highest eradication rates

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Section: Discussionmentioning

confidence: 97%

Randomized study comparing omeprazole with ranitidine as anti‐secretory agents combined in quadruple second‐line Helicobacter pylori eradication regimens

Michopoulos

Tsibouris

Bouzakis

et al. 2000

Aliment Pharmacol Ther

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“…then multiple biopsies (Sydney protocol) should be taken to increase the sensitivity. Because of the high cost of histology, biopsies should not be taken if the only purpose is to confirm H. pylori eradication [63][64][65]. UBT should be offered instead, and H. pylori eradication should be tested at least 2 weeks after PPI discontinuation and 4 weeks after stopping antibiotic and bismuth [38,61].…”

Section: Recommendation Grade: B; Evidence Level: 2b; Agreement Levelmentioning

confidence: 99%

Hellenic consensus on Helicobacter pylori infection

Georgopoulos

Michopoulos

Rokkas³

et al. 2020

aog

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The Hellenic Society of Gastroenterology recently organized the "Hellenic consensus on Helicobacter pylori (H. pylori) infection". The aim of this publication is to report the guidelines in order to aid the national gastroenterology community in the management of H. pylori infection. Forty-one delegates from all Greek regions, including gastroenterologists, pathologists, clinical microbiologists, epidemiologists and basic scientists, were invited to this meeting. The participants were allocated to 1 of the 4 main topics of the meeting: i.e., H. pylori diagnosis and association with diseases; H. pylori and gastric cancer; H. pylori and extragastric associated disorders; and H. pylori treatment. The results of each subgroup were submitted to a final consensus vote that included all participants. Relevant data based on international and Greek publications were presented, and the quality of evidence, strength of recommendation, and level of consensus were graded. The cutoff level of 70% was considered as acceptance for the final statement. It is hoped that the recommendations and conclusions of this report will guide Greek doctors in their daily practice concerning the management of H. pylori infection.

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Invasive methods and clinical follow-up to esimate HP eradication success

Cited by 2 publications

References 0 publications

Randomized study comparing omeprazole with ranitidine as anti‐secretory agents combined in quadruple second‐line Helicobacter pylori eradication regimens

Randomized study comparing omeprazole with ranitidine as anti‐secretory agents combined in quadruple second‐line Helicobacter pylori eradication regimens

Hellenic consensus on Helicobacter pylori infection

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