The 755-nm and 1,064-nm lasers, when compared with the 595-nm pulsed dye laser, can provide deeper penetration into the dermis, allowing for targeting of deeper and larger vessels. Photon absorption by hemoglobin at 755-nm is better than that at 1,064-nm; hence, more efficient vascular ablation can be induced when using 755-nm laser. However, 755-nm laser is highly absorbed by melanin, and it should be used in caution considering epidermal damage and threshold fluences for vascular clearance. Microsecond Nd:YAG laser is less painful with good safety profiles compared with the traditional millisecond Nd:YAG laser and pulsed dye laser. Accordingly, the dual wavelength long-pulsed 755-nm alexandrite/microsecond 1,064-nm Nd:YAG laser, together with has both advantages of each laser and can show benefits with complementary, synergistic effects in treating rosacea. Herein, we describe two patients with rosacea who were effectively treated with the dual wavelength long-pulsed 755-nm alexandrite/microsecond 1,064-nm Nd:YAG laser without noticeable side effects.
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