Inversion of T Waves on Admission is Associated with Mortality in Spontaneous Intracerebral Hemorrhage

Loggini, Andrea; Mansour, Ali; Ammar, Faten El; Tangonan, Ruth; Kramer, Christopher; Goldenberg, Fernando D.; Lazaridis, C.

doi:10.1016/j.jstrokecerebrovasdis.2021.105776

Cited by 5 publications

(2 citation statements)

References 24 publications

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“…Then, we examined the factors associated with ECG abnormalities. We found that hematoma volume and SIVH were the two strongest determinants of ECG abnormalities, which is consistent with the previous reports [15].…”

Section: Discussionsupporting

confidence: 93%

Changes of Electrocardiogram and Myocardial Enzymes in Patients with Intracerebral Hemorrhage

et al. 2022

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Purpose. Cardiac complications are common in patients with spontaneous intracerebral hemorrhage (ICH). The present study is aimed at observing the incidence of cardiac complications after ICH, so as at improving the understanding of the relationship between cardiac complications and ICH. Methods. This is a retrospective study on analyzing electrocardiogram (ECG) and serum myocardial enzyme of 208 patients with ICH admitted to a tertiary hospital from 2018 to 2019. For each patient, demographics, medical history, clinical presentation, ECG, serum myocardial enzyme, and head CT on admission were reviewed. Mortality was noted. Results. Among the 208 patients, 145 (69.71%) had one or more ECG abnormalities. The top three abnormalities were corrected QT interval (QTc) prolongation 52 (25%), ST depression 48 (23.08%), and T wave inversion 38 (18.27%). One hundred and thirty-nine patients (66.83%) had increased serum levels of at least one kind of myocardial enzyme, which were high-sensitive cardiac troponin T (hs-cTnT) 79 (37.98%), lactic dehydrogenase (LDH) 80 (38.46%), creatine kinase (CK) 57 (27.40%), and creatine kinase-myocardial subfraction (CKMB) 57 (27.40%). The logistic regression analysis showed the following: secondary intraventricular hemorrhage (SIVH) (odds ratio (OR) 5.32; 95% confidence interval (CI) 2.55–11.08; p < 0.001 ) and hematoma volume > 30 ml (OR 3.81; 95% CI 1.86–7.81; p < 0.001 ) were independent predictive factors of QTc prolongation; thalamus location (OR 5.79; 95% CI 1.94–17.28; p < 0.05 ), hematoma volume > 30 ml (OR 24.187; 95% CI 3.14-186.33; p < 0.05 ), insular involvement (OR 19.08; 95% CI 5.77-63.07; p < 0.001 ), and SIVH (OR 2.62; 95% CI 1.69-5.86; p < 0.05 ) were independent predictive factors of ST depression; insular involvement (OR 2.90; 95% CI 1.12–7.50; p < 0.05 ) and hematoma volume > 30 ml (OR 1.98; 95% CI 1.06–3.70; p < 0.05 ) were independent predictive factors of increase of CK; Glasgow Coma Scale (GCS) (OR 0.86; 95% CI 0.78–0.98; p < 0.05 ) and insular involvement (OR 5.56; 95% CI 1.98–15.62; p < 0.05 ) were independent predictive factors of increase of CKMB; SIVH (OR 2.05; 95% CI 1.07–3.92; p < 0.05 ) was independent predictive factor of increase of LDH; age (OR 1.03; 95% CI 1.01–1.06; p < 0.05 ), blood glucose on admission (OR 1.10; 95% CI 1.01–1.20; p < 0.05 ), and history of antiplatelet drug use (OR 3.50; 95% CI 1.01–12.12; p < 0.05 ) were independent predictive factors of hs-cTnT. All the injury indexes were not related to in-hospital mortality. Conclusion. The study suggests that insular involvement, hematoma volume > 30 ml, and SIVH are the strongest risk factors for ECG abnormalities and elevated myocardial enzymes after ICH followed which are the risk factors such as GCS, age, admission blood glucose, and ICH location in the thalamus.

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Section: Discussionsupporting

confidence: 93%

Changes of Electrocardiogram and Myocardial Enzymes in Patients with Intracerebral Hemorrhage

et al. 2022

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“…Multiple studies have demonstrated a correlation between cardiac arrhythmias and the risk of rebleeding in patients with cerebral hemorrhage. A clinical study of patients with cerebral hemorrhage, for instance, revealed a correlation between the presence of arrhythmias and the risk of mortality due to rebleeding [27,28]. Furthermore, another study involving patients with cerebral hemorrhage demonstrated a strong association between arrhythmias like atrial fibrillation and ventricular fibrillation with the risk of rebleeding [29,30].…”

Section: Heart Rhythm and Cerebral Hemorrhage Rebleedingmentioning

confidence: 99%

Predictive Value of Recurrent Acute Cerebral Hemorrhage: A Study Based on Electrocardiogram

2023

medsc

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Acute cerebral hemorrhage is a serious neurological disease with a high risk of recurrent bleeding. As a common clinical test, the importance of electrocardiogram in predicting recurrent bleeding in acute cerebral hemorrhage has gradually come to the fore. This paper provides a comprehensive review of the recent research progress in predicting recurrent bleeding in acute cerebral hemorrhage, emphasizing the application of electrocardiogram in this prediction and its clinical value.

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Electrocardiogram alterations in non-traumatic brain injury: a systematic review

Longhitano,

Bottinelli,

Pappalardo

et al. 2023

J Clin Monit Comput

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Inversion of T Waves on Admission is Associated with Mortality in Spontaneous Intracerebral Hemorrhage

Cited by 5 publications

References 24 publications

Changes of Electrocardiogram and Myocardial Enzymes in Patients with Intracerebral Hemorrhage

Changes of Electrocardiogram and Myocardial Enzymes in Patients with Intracerebral Hemorrhage

Predictive Value of Recurrent Acute Cerebral Hemorrhage: A Study Based on Electrocardiogram

Electrocardiogram alterations in non-traumatic brain injury: a systematic review

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