Investigating cell type specific mechanisms contributing to acute oral toxicity_suppl1

Abstract

workshops cosponsored by the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), the People for the Ethical Treatment of Animals (PETA) International Science Consortium Ltd, and the Physicians Committee for Responsible Medicine (PCRM) (Hamm et al., 2017;Clippinger et al., 2018a;Strickland et al., 2018). The relevant information is available at the PETA website 1 . In preclinical drug development, however, these studies are no longer required by default to support first clinical trials in humans (