Micro-archaeological data from sites located in central and eastern Europe show that, in comparison with other Upper Paleolithic hunter-gatherers, Gravettian foragers used fire more intensively and for a wider range of purposes. At these sites, this shift in pyrotechnology overlaps with the onset of periglacial conditions. Gravettian occupations of non-periglacial regions have been poorly investigated with micro-archaeological methods, and it remains to be further demonstrated whether these foragers also made a similar intensive and multipurpose use of fire. To further investigate this topic, we studied the sequence preserved at the cave of Fuente del Salín, in Cantabria, where previous excavations unearthed potential fire residues of Gravettian age. Using micromorphology, µ-X-ray fluorescence, and Scanning Electron Microscopy we reconstructed multiple phases of human visits to the site. Our results show that, during the main Gravettian occupation, foragers made intensive use of fire, as indicated by abundant heated bones and seashells, charcoals, amorphous char, fat-derived char, and in situ remains of potential stacked open hearths as well as burnt grass beddings. The intensive burning, systematic reuse of combustion features, and multiple purposes of the fires at Fuente del Salín are comparable with Gravettian sites from central and eastern Europe, indicating that these fire-use behaviors probably do not reflect a regional adaptation to periglacial environments but a cultural trait of the Gravettian tradition across Europe.