Investigating the Factors Affecting the Development of Biliary Pancreatitis and Their Relationship with the Type and Severity of Complications

Pirouz, Amirhossein; Sadeghian, Ehsan; Jafari, Mehdi; Eslamian, Reza; Elyasinia, Fezzeh; Mohammadi-Vajari, Mohammad-Ali; Abdehgah, Ali Ghorbani; Soroush, Ahmadreza

doi:10.34172/mejdd.2021.202

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Acute biliary pancreatitis (ABP) is a common emergency in the department of gastroenterology, which is mainly caused by self-digestion of pancreatic tissue, pancreatic fluid overflow, impaired pancreatic mucosal barrier, and obstruction of pancreatic duct caused by inflammation and biliary calculi. The main clinical manifestations are jaundice, abdominal distension, and abdominal pain [ 1 ]. ABP can also cause bleeding and shock, which requires active and effective treatment; otherwise, it may lead to death [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

CRP and ALT Levels in Individuals with Acute Biliary Pancreatitis after Endoscopic Retrograde Cholangiopancreatography and Endoscopic Sphincterotomy

Zhu

Sun

2022

Computational Intelligence and Neuroscience

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Objective. The goal of this study was to see how effective endoscopic retrograde cholangiopancreatography combined with endoscopic sphincterotomy was in treating acute biliary pancreatitis and how it affected CRP and ALT levels. Methods. This analysis is based on a 100-patient acute pancreatitis (ABP) study conducted at our institution from June 2019 to June 2020. They were divided into two groups of 50 cases each, the control group and the observational group, according to the random number table. Endoscopic sphincterotomy and ERCP were performed on the observation group instead of open surgery on the control group as a point of comparison (EST). The followings were compared including abdominal pain relief duration, blood amylase recovery duration, and hospital stay duration, as well as Serum C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) level; the ALT, AST, and GGT levels of the two groups were compared, as well as the occurrence of problems in both groups. Results. The observation group had a significantly shorter duration of abdominal pain, blood amylase recovery, and hospital stay. Presurgery CRP, IL-6, and TNF-α levels in both groups were significantly lower in the observation group than in the control group. According to the results of the study, both groups saw significant decreases in ALT, AST, and GGT after surgery; however, the levels of these markers in both groups were significantly lower in the observation group after surgery than in the control group. The observation group’s (14.00 percent) complication rate was substantially lower. Conclusion. ERCP and EST in the treatment of ABP can not only successfully improve clinical indexes and facilitate the recovery of patients but also reduce the levels of CRP and alt, reduce the level of inflammation, and enhance renal function, with reduced problems, which has a high clinical reference value.

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Section: Introductionmentioning

confidence: 99%

CRP and ALT Levels in Individuals with Acute Biliary Pancreatitis after Endoscopic Retrograde Cholangiopancreatography and Endoscopic Sphincterotomy

Zhu

Sun

2022

Computational Intelligence and Neuroscience

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Histological Features of the Hepatic and Pancreatic Structure of Female Rats in the Model of Biliary Pancreatitis with Hyperprolactinemia

Sirotina,

Ilieva,

Rudenko

et al. 2024

J Evol Biochem Phys

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Retrospective Evaluation of Clinical and Biochemical Data in Patients with Pancreatic Conditions

Moezzi,

Afshari,

Seyedian

et al. 2024

Jundishapur J Chronic Dis Care

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Background: Pancreatic inflammation, also known as pancreatitis, occurs when exocrine pancreatic enzymes infiltrate the pancreas and cause pathological inflammation. Each case of acute pancreatitis is associated with a subset of causes, indicating the presence of known risk factors. Objectives: This paper aims to identify the common causes of pancreatitis and the factors affecting hospitalization and survival at the study site. Methods: Data were collected from the hospital information systems (HIS) using the K85 code from the International Statistical Classification of Diseases 10 (ICD10) at a referral center in Ahvaz, Iran. Demographic information, comorbidities, laboratory parameters, and paraclinical information such as ultrasound documents and reports were gathered. The study focuses on demonstrating the common causes of pancreatitis and factors impacting hospitalization and survival rates from 2017 to 2020. Results: During this period, 84 patients were admitted. The highest number of admissions occurred in 2020, with the majority of patients being 40 - 60 years old, and women constituting a larger proportion. In total, 85.7% of patients were hospitalized for less than 10 days. About 92% were discharged with follow-up advice, while the rest were discharged against medical advice (DAMA). No deaths were recorded during this period due to pancreatitis. Conclusions: The most common comorbidities in this study were gallstones, sludge, and a BMI exceeding 30. Additionally, elevated levels of glucose, creatinine, amylase, and lactate dehydrogenase were associated with prolonged hospitalization.

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Investigating the Factors Affecting the Development of Biliary Pancreatitis and Their Relationship with the Type and Severity of Complications

Cited by 3 publications

References 9 publications

CRP and ALT Levels in Individuals with Acute Biliary Pancreatitis after Endoscopic Retrograde Cholangiopancreatography and Endoscopic Sphincterotomy

CRP and ALT Levels in Individuals with Acute Biliary Pancreatitis after Endoscopic Retrograde Cholangiopancreatography and Endoscopic Sphincterotomy

Histological Features of the Hepatic and Pancreatic Structure of Female Rats in the Model of Biliary Pancreatitis with Hyperprolactinemia

Retrospective Evaluation of Clinical and Biochemical Data in Patients with Pancreatic Conditions

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