Abstract:Amyloid is defined as insoluble, extracellular, proteinous aggregates formed by misfolding of proteins or peptides which are normally soluble. In the human body, amyloid is toxic and can cause cell death. Therefore, the presence of amyloid is linked with several diseases, including Alzheimer's disease (AD), spongiform encephalopathies and type II diabetes, which are also referred as amyloidosis. AD is one of the most well-known amyloidoses. In AD, the amyloid aggregates appear predominantly in the patients' br… Show more
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